An injectable self-assembling hydrogel based on RGD peptidomimetic β-sheets as multifunctional biomaterials.

Biocompatible Materials Hydrogels / chemistry Methicillin-Resistant Staphylococcus aureus Oligopeptides / pharmacology Peptides / chemistry Peptidomimetics / pharmacology Protein Conformation, beta-Strand
3D scaffold Antimicrobial Cell adhesive Hydrogel RGD mimic

Journal

Biomaterials advances
ISSN: 2772-9508
Titre abrégé: Biomater Adv
Pays: Netherlands
ID NLM: 9918383886206676

Informations de publication

Date de publication:
Feb 2022
Historique:
received: 14 09 2021
revised: 09 12 2021
accepted: 20 12 2021
pubmed: 9 5 2022
medline: 3 8 2022
entrez: 8 5 2022
Statut: ppublish

Résumé

Ability of the cells to adhere to an extracellular material is central to successful tissue genesis. Arg-Gly-Asp (RGD) sequences found in extracellular matrix proteins are well known for cell adhesion, however, enzymatic degradation and lack of specificity have limited their widespread use. Besides, a multifunctional material with inherent antimicrobial ability would help in invigorating the practical tissue engineering applications. Here, we report novel modified RGD (M

Identifiants

DOI: 10.1016/j.msec.2021.112633 PMID: 35527136
pubmed: 35527136
pii: S0928-4931(21)00773-6
doi: 10.1016/j.msec.2021.112633
pii:
doi:

Substances chimiques

Biocompatible Materials 0
Hydrogels 0
Oligopeptides 0
Peptides 0
Peptidomimetics 0
arginyl-glycyl-aspartic acid 78VO7F77PN

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

112633

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Zeba Ahmadi (Z)

Nucleic Acids Research Laboratory, CSIR-Institute of Genomics and Integrative Biology, Mall Road, Delhi 110007, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.

Santosh Yadav (S)

Nucleic Acids Research Laboratory, CSIR-Institute of Genomics and Integrative Biology, Mall Road, Delhi 110007, India.

Aditya Kumar Kar (AK)

Nanomaterial Toxicology Laboratory, CSIR-Indian Institute of Toxicology Research, Mahatma Gandhi Marg, Lucknow 226 001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.

Diksha Jha (D)

Microbial Biotechnology Laboratory, CSIR-Institute of Genomics and Integrative Biology, Sukhdev Vihar, New Delhi 110025, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.

Hemant Kumar Gautam (HK)

Microbial Biotechnology Laboratory, CSIR-Institute of Genomics and Integrative Biology, Sukhdev Vihar, New Delhi 110025, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.

Satyakam Patnaik (S)

Nanomaterial Toxicology Laboratory, CSIR-Indian Institute of Toxicology Research, Mahatma Gandhi Marg, Lucknow 226 001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.

Pradeep Kumar (P)

Nucleic Acids Research Laboratory, CSIR-Institute of Genomics and Integrative Biology, Mall Road, Delhi 110007, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India. Electronic address: pkumar@igib.res.in.

Ashwani Kumar Sharma (AK)

Nucleic Acids Research Laboratory, CSIR-Institute of Genomics and Integrative Biology, Mall Road, Delhi 110007, India. Electronic address: ashwani@igib.in.

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Classifications MeSH

questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Matériaux biocompatibles › An injectable self-assembling hydrogel based...
questionsmedicales.fr › Préparations pharmaceutiques › Colloïdes › Gels › Hydrogels › An injectable self-assembling hydrogel based...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Cocci à Gram positif › Staphylococcaceae › Staphylococcus › Staphylococcus aureus › Staphylococcus aureus résistant à la méticilline › An injectable self-assembling hydrogel based...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Oligopeptides › An injectable self-assembling hydrogel based...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › An injectable self-assembling hydrogel based...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Peptidomimétiques › An injectable self-assembling hydrogel based...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structure secondaire des protéines › Structure en brin bêta › An injectable self-assembling hydrogel based...