Concomitant presentation of spontaneous coronary artery dissection with Takotsubo syndrome: a case report.

Acute coronary syndrome Case report Left ventricular apical ballooning Spontaneous coronary artery dissection Takotsubo syndrome

Journal

European heart journal. Case reports
ISSN: 2514-2119
Titre abrégé: Eur Heart J Case Rep
Pays: England
ID NLM: 101730741

Informations de publication

Date de publication:
May 2022
Historique:
received: 31 10 2021
revised: 31 12 2021
accepted: 14 04 2022
entrez: 9 5 2022
pubmed: 10 5 2022
medline: 10 5 2022
Statut: epublish

Résumé

Spontaneous coronary artery dissection (SCAD) is still an underdiagnosed condition that requires a detailed assessment of angiographic signs. It also shares similar clinical presentations with Takotsubo syndrome (TTS). The concomitant presentation of SCAD with TTS is a possible occurrence, making it difficult for clinicians to treat and manage. This study included a 49-year-old woman with retrosternal chest pain who was admitted to the emergency department. Coronary angiography indicated Type 2A SCAD involving the middle part of the left anterior descending artery, while the left ventriculography indicated a typical left ventricular apical ballooning compatible with TTS. A conservative approach to the management of SCAD was observed. After a 3-month follow-up, the control coronary angiography showed a complete angiographic resolution. The results of the transthoracic echocardiogram (TTE) and cardiac magnetic resonance revealed a complete normalization of the pathological features. The patient remained asymptomatic and showed no recurrence of chest pain. Although TTS and SCAD are commonly observed in patients who share certain characteristics (women, without atheromatous terrain, stress-related factors), it is difficult to establish a pathophysiological link between them. This observation confirms the non-random association of two rare entities of myocardial infarction with no obstructive coronary arteries. Although TTS can be easily diagnosed via non-invasive imaging, the diagnosis of SCAD is more difficult. The findings of this study suggest a concomitant presentation between SCAD and TTS. Although the treatment approach to SCAD is usually conservative, severe forms of this disease require early diagnosis and appropriate treatment.

Sections du résumé

Background UNASSIGNED
Spontaneous coronary artery dissection (SCAD) is still an underdiagnosed condition that requires a detailed assessment of angiographic signs. It also shares similar clinical presentations with Takotsubo syndrome (TTS). The concomitant presentation of SCAD with TTS is a possible occurrence, making it difficult for clinicians to treat and manage.
Case summary UNASSIGNED
This study included a 49-year-old woman with retrosternal chest pain who was admitted to the emergency department. Coronary angiography indicated Type 2A SCAD involving the middle part of the left anterior descending artery, while the left ventriculography indicated a typical left ventricular apical ballooning compatible with TTS. A conservative approach to the management of SCAD was observed. After a 3-month follow-up, the control coronary angiography showed a complete angiographic resolution. The results of the transthoracic echocardiogram (TTE) and cardiac magnetic resonance revealed a complete normalization of the pathological features. The patient remained asymptomatic and showed no recurrence of chest pain.
Discussion UNASSIGNED
Although TTS and SCAD are commonly observed in patients who share certain characteristics (women, without atheromatous terrain, stress-related factors), it is difficult to establish a pathophysiological link between them. This observation confirms the non-random association of two rare entities of myocardial infarction with no obstructive coronary arteries. Although TTS can be easily diagnosed via non-invasive imaging, the diagnosis of SCAD is more difficult. The findings of this study suggest a concomitant presentation between SCAD and TTS. Although the treatment approach to SCAD is usually conservative, severe forms of this disease require early diagnosis and appropriate treatment.

Identifiants

pubmed: 35528117
doi: 10.1093/ehjcr/ytac172
pii: ytac172
pmc: PMC9071323
doi:

Types de publication

Case Reports

Langues

eng

Pagination

ytac172

Informations de copyright

© The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology.

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Auteurs

Simon Fitouchi (S)

Division of Cardiovascular Medicine, Cardiovascular Institute, Strasbourg, France.
Division of Cardiovascular Medicine, University Hospital of Strasbourg, Strasbourg, France.

Paola Di Marco (P)

Division of Cardiovascular Medicine, Cardiovascular Institute, Strasbourg, France.

Pascal Motreff (P)

Department of Cardiology, Gabriel Montpied Hospital, Clermont-Ferrand University Hospital, Clermont-Ferrand, France.
Clermont Université, Université d'Auvergne, Cardio Vascular Interventional Therapy and Imaging (CaVITI), Image Science for Interventional Techniques (ISIT), Clermont-Ferrand, France.

Nicolas Lhoest (N)

Division of Cardiovascular Medicine, Cardiovascular Institute, Strasbourg, France.

Classifications MeSH