Study of selected genes of Wnt signaling pathway in relation to the parameters in the bone tissue of the laying hens.
Bone
Laying hens
Osteoporosis
Polymorphism
Wnt signaling pathway
Journal
Saudi journal of biological sciences
ISSN: 1319-562X
Titre abrégé: Saudi J Biol Sci
Pays: Saudi Arabia
ID NLM: 101543796
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
received:
22
10
2021
revised:
29
11
2021
accepted:
12
12
2021
entrez:
9
5
2022
pubmed:
10
5
2022
medline:
10
5
2022
Statut:
ppublish
Résumé
The Wnt signaling pathway plays a critical role in almost all aspects of skeletal development and homeostasis. Many studies suggest the importance of this signaling pathway in connection with bone metabolism through many skeletal disorders caused by mutations in Wnt signaling genes. The knowledge gained through targeting this pathway is of great value for skeletal health and diseases, for example of increased bone mass in the case of osteoporosis. Our objective was to focus on the detection of single nucleotide polymorphisms and investigate the associations between possible polymorphisms in selected genes that are part of those signaling pathways and parameters of bones in hens of ISA Brown hybrids (bone breaking strength, length, width, and bone mass). Different regions of the
Identifiants
pubmed: 35531234
doi: 10.1016/j.sjbs.2021.12.024
pii: S1319-562X(21)01057-3
pmc: PMC9072936
doi:
Types de publication
Journal Article
Langues
eng
Pagination
2526-2531Informations de copyright
© 2021 The Author(s).
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Références
Int J Mol Sci. 2019 Apr 04;20(7):
pubmed: 30987410
J Anim Sci Biotechnol. 2015 Dec 22;6:55
pubmed: 26702356
PLoS One. 2017 Apr 3;12(4):e0174808
pubmed: 28369098
Bone Res. 2019 Jul 8;7:19
pubmed: 31646011
Calcif Tissue Int. 2009 Jun;84(6):439-45
pubmed: 19424741
Maturitas. 2014 Jul;78(3):233-7
pubmed: 24815296
PLoS One. 2013 Oct 22;8(10):e76960
pubmed: 24167553
Cell Mol Life Sci. 2013 Nov;70(21):4023-37
pubmed: 23516016
Bone. 2011 Sep;49(3):343-8
pubmed: 21645651
J Anim Sci. 2018 Jun 29;96(7):2525-2535
pubmed: 29701819
Int J Mol Sci. 2020 Nov 05;21(21):
pubmed: 33167497
Injury. 2016 Jun;47 Suppl 2:S11-20
pubmed: 27338221
Bone Res. 2021 Apr 29;9(1):23
pubmed: 33927194
JBMR Plus. 2021 Mar 19;5(5):e10481
pubmed: 33977200
Front Cell Dev Biol. 2021 Jan 21;9:631623
pubmed: 33585487
Front Cell Dev Biol. 2019 Jan 07;6:170
pubmed: 30666305
Front Endocrinol (Lausanne). 2019 Feb 25;10:70
pubmed: 30858824
J Bone Miner Res. 2013 May;28(5):1150-9
pubmed: 23188710
Front Physiol. 2020 Feb 05;11:47
pubmed: 32116759
Toxicol Pathol. 2017 Oct;45(7):864-868
pubmed: 29105581
Bone. 2018 Mar;108:132-144
pubmed: 29307778
Am J Pathol. 2016 Jun;186(6):1598-609
pubmed: 27083516
Hum Genomics. 2010 Jun;4(5):284-8
pubmed: 20650817
Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):E2197-204
pubmed: 22745162
Sci Rep. 2017 Apr 06;7:45317
pubmed: 28383518
J Bone Miner Metab. 2010 Nov;28(6):696-705
pubmed: 20407796
PLoS Genet. 2015 May 29;11(5):e1005250
pubmed: 26023928