Respiratory complications and sleep disorders in children with chronic kidney disease: A correlation often underestimated.

Central apnoea Chronic kidney disease End-stage renal disease Hypoventilation Lung function Quality of life Sleep-disordered breathing

Journal

Paediatric respiratory reviews
ISSN: 1526-0550
Titre abrégé: Paediatr Respir Rev
Pays: England
ID NLM: 100898941

Informations de publication

Date de publication:
Mar 2023
Historique:
received: 07 10 2021
revised: 09 11 2021
accepted: 02 12 2021
pubmed: 10 5 2022
medline: 15 3 2023
entrez: 9 5 2022
Statut: ppublish

Résumé

Chronic Kidney Disease (CKD) is characterized by a progressive and irreversible loss of kidney function which gradually leads to end-stage kidney disease (ESKD). Virtually all the organs are damaged by the toxicity of uremic compounds. The lungs may be affected and the impaired pulmonary function may be the direct result of fluid retention and metabolic, endocrine and cardiovascular alterations, as well as systemic activation of the inflammation. An increased prevalence in sleep disorders (SD) is also reported in patients with CKD, leading to a further negative impact on overall health and quality of life. While these complex relationships are well documented in the adult population, these aspects remain relatively little investigated in children. The aim of this review is to provide a brief overview of the pathophysiology between lung and kidney and to summarize how CKD may affect respiratory function and sleep in children.

Identifiants

pubmed: 35534343
pii: S1526-0542(22)00008-2
doi: 10.1016/j.prrv.2021.12.003
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

16-22

Informations de copyright

Copyright © 2022 Elsevier Ltd. All rights reserved.

Auteurs

M Lelii (M)

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Pediatric Highly Intensive Care Unit, via della Commenda 9, 20122 Milan, Italy. Electronic address: mara.lelii@policlinico.mi.it.

L Senatore (L)

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Pediatric Highly Intensive Care Unit, via della Commenda 9, 20122 Milan, Italy.

F Paglialonga (F)

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Pediatric Nephrology, Dialysis and Transplant Unit, Via della Commenda 9, 20122 Milan, Italy. Electronic address: fabio.paglialonga@policlinico.mi.it.

S Consolo (S)

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Pediatric Nephrology, Dialysis and Transplant Unit, Via della Commenda 9, 20122 Milan, Italy. Electronic address: silvia.consolo@policlinico.mi.it.

G Montini (G)

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Pediatric Nephrology, Dialysis and Transplant Unit, Via della Commenda 9, 20122 Milan, Italy; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy. Electronic address: giovanni.montini@policlinico.mi.it.

A Rocchi (A)

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Pediatric Emergency Department, via della Commenda 9, 20122 Milan, Italy. Electronic address: alessia.rocchi@policlinico.mi.it.

P Marchisio (P)

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Pediatric Highly Intensive Care Unit, via della Commenda 9, 20122 Milan, Italy; Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy. Electronic address: paola.marchisio@policlinico.mi.it.

M F Patria (MF)

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Pediatric Highly Intensive Care Unit, via della Commenda 9, 20122 Milan, Italy. Electronic address: francesca.patria@policlinico.mi.it.

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