Molecular docking analysis of piperlongumine with different apoptotic proteins involved in Hepatocellular Carcinoma.

AutoDock Hepatocellular Carcinoma Molecular Docking Piperlongumine Vascular Endothelial Growth Factor

Journal

Bioinformation
ISSN: 0973-2063
Titre abrégé: Bioinformation
Pays: Singapore
ID NLM: 101258255

Informations de publication

Date de publication:
2021
Historique:
received: 23 07 2021
revised: 21 09 2021
accepted: 21 09 2021
entrez: 11 5 2022
pubmed: 12 5 2022
medline: 12 5 2022
Statut: epublish

Résumé

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer. Numerous signalling pathways are involved in hepatocellular carcinoma. Piperlongumine is a potential candidate for the treatment of hepatocellular carcinoma. Therefore, it is of interest to document the molecular docking analysis of piperlongumine with different apoptotic proteins involved in Hepatocellular Carcinoma. Piperlongumine was docked with the HCC targets such as vascular endothelial growth factor (VEGF), epidermal growth factor receptor, Aurora-2, Nuclear factor Kappa-B (NF-KB), Jak2 Kinase, Fibroblast growth factor receptor 4, Bcl-2-like protein 1,Apopain, and Apoptosis regulator Bcl-2 using

Identifiants

pubmed: 35539886
doi: 10.6026/97320630017829
pii: 97320630017829
pmc: PMC9049083
doi:

Types de publication

Journal Article

Langues

eng

Pagination

829-833

Informations de copyright

© 2021 Biomedical Informatics.

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Auteurs

Ashish Kumar (A)

Department of Biochemistry, All India Institute of Medical Sciences (AIIMS), Rishikesh-249203, Uttarakhand, India.

Ambika Sharma (A)

Department of Biochemistry, College of Veterinary Science, DUVASU, Mathura-281001, Uttar Pradesh, India.

Shailendra Handu (S)

Department of Pharmacology, All India Institute of Medical Sciences (AIIMS), Rishikesh-249203, Uttarakhand, India.

Jagjit Singh (J)

Department of Pharmacology, All India Institute of Medical Sciences (AIIMS), Rishikesh-249203, Uttarakhand, India.

Manisha Naithani (M)

Department of Biochemistry, All India Institute of Medical Sciences (AIIMS), Rishikesh-249203, Uttarakhand, India.

Classifications MeSH