The protective effect of propofol on ionizing radiation-induced hematopoietic system damage in mice.
Journal
RSC advances
ISSN: 2046-2069
Titre abrégé: RSC Adv
Pays: England
ID NLM: 101581657
Informations de publication
Date de publication:
04 Nov 2019
04 Nov 2019
Historique:
received:
10
09
2019
revised:
19
11
2019
accepted:
26
10
2019
entrez:
11
5
2022
pubmed:
8
11
2019
medline:
8
11
2019
Statut:
epublish
Résumé
The hematopoietic system is highly sensitive to ionizing radiation (IR), and IR can cause injury to hematopoietic stem cells (HSCs); the main reason for this may be elevated reactive oxygen species (ROS) levels. Propofol is an anesthetic drug commonly used in clinical practice. The chemical structure of propofol is similar to that of vitamin E, and propofol has an antioxidant capacity. Therefore, in this work the effect of using propofol to protect against IR-induced hematopoietic system injury is evaluated. The data suggested that when the irradiated mice were treated with 20 mg kg
Identifiants
pubmed: 35540614
doi: 10.1039/c9ra07262d
pii: c9ra07262d
pmc: PMC9075036
doi:
Types de publication
Journal Article
Langues
eng
Pagination
36366-36373Commentaires et corrections
Type : ErratumIn
Informations de copyright
This journal is © The Royal Society of Chemistry.
Déclaration de conflit d'intérêts
There are no conflicts to declare.
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