Hexachlorobenzene exerts genotoxic effects in a humpback whale cell line under stable exposure conditions.


Journal

RSC advances
ISSN: 2046-2069
Titre abrégé: RSC Adv
Pays: England
ID NLM: 101581657

Informations de publication

Date de publication:
27 Nov 2019
Historique:
received: 12 07 2019
accepted: 15 11 2019
entrez: 11 5 2022
pubmed: 29 11 2019
medline: 29 11 2019
Statut: epublish

Résumé

Humpback whales, like other polar wildlife, accumulate persistent organic pollutants. In Southern hemisphere populations, hexachlorobenzene (HCB) dominates the contaminant profiles. HCB is linked to a variety of health effects and is classified as a group 2B carcinogen, but the mechanism of action is a matter of contention. Potential toxicological effects to humpback whales remain entirely unknown. The recently established humpback whale fibroblast cell line (HuWa) offers an

Identifiants

pubmed: 35540658
doi: 10.1039/c9ra05352b
pii: c9ra05352b
pmc: PMC9076109
doi:

Types de publication

Journal Article

Langues

eng

Pagination

39447-39457

Informations de copyright

This journal is © The Royal Society of Chemistry.

Déclaration de conflit d'intérêts

There are no conflicts to declare.

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Auteurs

Jenny Maner (J)

Department Environmental Toxicology, Eawag, Swiss Federal Institute of Aquatic Science and Technology 8600 Dübendorf Switzerland kristin.schirmer@eawag.ch.
Department of Environmental Systems Science, ETH Zürich 8092 Zürich Switzerland.

Michael Burkard (M)

Department Environmental Toxicology, Eawag, Swiss Federal Institute of Aquatic Science and Technology 8600 Dübendorf Switzerland kristin.schirmer@eawag.ch.
Southern Ocean Persistent Organic Pollutants Program, Environmental Futures Research Institute, Griffith University Brisbane QLD 4108 Australia.

Juan Carlos Cassano (JC)

Empa, Swiss Laboratories for Material Science and Technology, Particle-Biology Interactions Laboratory 9014 St Gallen Switzerland.

Susan M Bengtson Nash (SMB)

Southern Ocean Persistent Organic Pollutants Program, Environmental Futures Research Institute, Griffith University Brisbane QLD 4108 Australia.

Kristin Schirmer (K)

Department Environmental Toxicology, Eawag, Swiss Federal Institute of Aquatic Science and Technology 8600 Dübendorf Switzerland kristin.schirmer@eawag.ch.
Department of Environmental Systems Science, ETH Zürich 8092 Zürich Switzerland.
School of Architecture, Civil and Environmental Engineering, EPF Lausanne 1015 Lausanne Switzerland.

Marc J-F Suter (MJ)

Department Environmental Toxicology, Eawag, Swiss Federal Institute of Aquatic Science and Technology 8600 Dübendorf Switzerland kristin.schirmer@eawag.ch.
Department of Environmental Systems Science, ETH Zürich 8092 Zürich Switzerland.

Classifications MeSH