Dichotomous role of miR193b-3p in diabetic foot ulcers maintains inhibition of healing and suppression of tumor formation.

Animals Carcinoma, Squamous Cell Cell Movement / genetics Diabetes Mellitus Diabetic Foot / genetics Mice Skin Neoplasms Wound Healing

Journal

Science translational medicine
ISSN: 1946-6242
Titre abrégé: Sci Transl Med
Pays: United States
ID NLM: 101505086

Informations de publication

Date de publication:
11 05 2022
Historique:
entrez: 11 5 2022
pubmed: 12 5 2022
medline: 18 5 2022
Statut: ppublish

Résumé

Despite the hyperproliferative environment marked by activation of β-catenin and overexpression of

Identifiants

DOI: 10.1126/scitranslmed.abg8397 PMID: 35544594 PMC: PMC9707408
pubmed: 35544594
doi: 10.1126/scitranslmed.abg8397
pmc: PMC9707408
mid: NIHMS1840047
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

eabg8397

Subventions

Organisme : NCI NIH HHS
ID : R01 CA166835
Pays : United States
Organisme : NINR NIH HHS
ID : R01 NR015649
Pays : United States
Organisme : NIAMS NIH HHS
ID : R01 AR073614
Pays : United States
Organisme : NIDDK NIH HHS
ID : RC1 DK086364
Pays : United States
Organisme : NIDDK NIH HHS
ID : U01 DK119085
Pays : United States
Organisme : NIDDK NIH HHS
ID : U24 DK115255
Pays : United States

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Auteurs

Jelena Marjanovic (J)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
ORCID: 0000-0003-2770-3083

Horacio A Ramirez (HA)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.

Ivan Jozic (I)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
ORCID: 0000-0001-5114-9524

Rivka C Stone (RC)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
ORCID: 0000-0002-7489-2123

Tongyu C Wikramanayake (TC)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
ORCID: 0000-0001-6307-7986

Cheyanne R Head (CR)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
ORCID: 0000-0001-9527-1337

Beatriz Abdo Abujamra (B)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
ORCID: 0000-0001-8619-9273

Nkemcho Ojeh (N)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
Faculty of Medical Sciences, The University of the West Indies, Bridgetown BB11000, Barbados.
ORCID: 0000-0002-2507-2209

Robert S Kirsner (RS)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136 USA.

Hadar Lev-Tov (H)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
ORCID: 0000-0001-6223-7001

Irena Pastar (I)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
ORCID: 0000-0003-0197-6198

Marjana Tomic-Canic (M)

Wound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.
ORCID: 0000-0002-9341-0193

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Dichotomous role of miR193b-3p in diabetic...
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs épithéliales épidermoïdes et glandulaires › Tumeurs épidermoïdes › Carcinome épidermoïde › Dichotomous role of miR193b-3p in diabetic...
questionsmedicales.fr › Phénomènes physiologiques › Mouvement cellulaire › Dichotomous role of miR193b-3p in diabetic...
questionsmedicales.fr › Maladies endocriniennes › Diabète › Dichotomous role of miR193b-3p in diabetic...
questionsmedicales.fr › Maladies endocriniennes › Diabète › Complications du diabète › Neuropathies diabétiques › Pied diabétique › Dichotomous role of miR193b-3p in diabetic...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Dichotomous role of miR193b-3p in diabetic...
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Tumeurs cutanées › Dichotomous role of miR193b-3p in diabetic...
questionsmedicales.fr › Phénomènes biologiques › Régénération › Cicatrisation de plaie › Dichotomous role of miR193b-3p in diabetic...