COVID-19 and retinal degenerative diseases: Promising link "Kaempferol".

Aged Flavonoids / therapeutic use Humans Kaempferols / pharmacology Macular Degeneration / drug therapy Retina / metabolism Retinal Diseases / drug therapy COVID-19 Drug Treatment

Journal

Current opinion in pharmacology
ISSN: 1471-4973
Titre abrégé: Curr Opin Pharmacol
Pays: England
ID NLM: 100966133

Informations de publication

Date de publication:
06 2022
Historique:
received: 31 12 2021
revised: 10 03 2022
accepted: 24 03 2022
pubmed: 12 5 2022
medline: 7 6 2022
entrez: 11 5 2022
Statut: ppublish

Résumé

Coronavirus disease (COVID-19) outbreak has caused unprecedented global disruption since 2020. Approximately 238 million people are affected worldwide where the elderly succumb to mortality. Post-COVID syndrome and its side effects have popped up with several health hazards, such as macular degeneration and vision loss. It thus necessitates better medical care and management of our dietary practices. Natural flavonoids have been included in traditional medicine and have also been used safely against COVID-19 and several other diseases. Kaempferol is an essential flavonoid that has been demonstrated to influence several vital cellular signaling pathways involved in apoptosis, angiogenesis, inflammation, and autophagy. In this review, we emphasize the plausible regulatory effects of Kaempferol on hallmarks of COVID-19 and macular degeneration.

Identifiants

DOI: 10.1016/j.coph.2022.102231 PMID: 35544976 PMC: PMC9080119
pubmed: 35544976
pii: S1471-4892(22)00058-3
doi: 10.1016/j.coph.2022.102231
pmc: PMC9080119
pii:
doi:

Substances chimiques

Flavonoids 0
Kaempferols 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

102231

Informations de copyright

Copyright © 2022 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of interest statement Nothing declared.

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Auteurs

Arman Firoz (A)

Apoptosis and Cell Survival Research Laboratory, 412G Pearl Research Park, School of Biosciences and Technology, Vellore Institute of Technology, Vellore, 632014, Tamil Nadu, India.

Priti Talwar (P)

Apoptosis and Cell Survival Research Laboratory, 412G Pearl Research Park, School of Biosciences and Technology, Vellore Institute of Technology, Vellore, 632014, Tamil Nadu, India. Electronic address: priti.t@vit.ac.in.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › COVID-19 and retinal degenerative diseases:...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzopyranes › 4H-1-Benzopyran-4-ones › Flavonoïdes › COVID-19 and retinal degenerative diseases:...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › COVID-19 and retinal degenerative diseases:...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzopyranes › 4H-1-Benzopyran-4-ones › Flavonoïdes › Flavonols › Kaempférols › COVID-19 and retinal degenerative diseases:...
questionsmedicales.fr › Maladies de l'oeil › Rétinopathies › Dégénérescence de la rétine › Dégénérescence maculaire › COVID-19 and retinal degenerative diseases:...
questionsmedicales.fr › Organes des sens › Oeil › Rétine › COVID-19 and retinal degenerative diseases:...
questionsmedicales.fr › Maladies de l'oeil › Rétinopathies › COVID-19 and retinal degenerative diseases:...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Traitements médicamenteux de la COVID-19 › COVID-19 and retinal degenerative diseases:...