Combining genomic and epidemiological data to compare the transmissibility of SARS-CoV-2 variants Alpha and Iota.


Journal

Communications biology
ISSN: 2399-3642
Titre abrégé: Commun Biol
Pays: England
ID NLM: 101719179

Informations de publication

Date de publication:
11 05 2022
Historique:
received: 06 12 2021
accepted: 06 04 2022
entrez: 11 5 2022
pubmed: 12 5 2022
medline: 18 5 2022
Statut: epublish

Résumé

SARS-CoV-2 variants shaped the second year of the COVID-19 pandemic and the discourse around effective control measures. Evaluating the threat posed by a new variant is essential for adapting response efforts when community transmission is detected. In this study, we compare the dynamics of two variants, Alpha and Iota, by integrating genomic surveillance data to estimate the effective reproduction number (R

Identifiants

pubmed: 35545661
doi: 10.1038/s42003-022-03347-3
pii: 10.1038/s42003-022-03347-3
pmc: PMC9095641
doi:

Banques de données

figshare
['10.6084/m9.figshare.c.5928089']

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural Research Support, U.S. Gov't, P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

439

Subventions

Organisme : NHLBI NIH HHS
ID : T35 HL007649
Pays : United States
Organisme : NCATS NIH HHS
ID : TL1 TR001864
Pays : United States

Commentaires et corrections

Type : UpdateOf

Informations de copyright

© 2022. The Author(s).

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Auteurs

Mary E Petrone (ME)

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06510, USA. mary.petrone@yale.edu.

Jessica E Rothman (JE)

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06510, USA.

Mallery I Breban (MI)

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06510, USA.

Isabel M Ott (IM)

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06510, USA.

Alexis Russell (A)

Wadsworth Center, New York State Department of Health, Albany, NY, 12208, USA.

Erica Lasek-Nesselquist (E)

Wadsworth Center, New York State Department of Health, Albany, NY, 12208, USA.
Department of Biomedical Sciences, University at Albany, SUNY, Albany, NY, 12222, USA.

Hamada Badr (H)

Department of Civil and Systems Engineering, Johns Hopkins University, Baltimore, 21218, MD, USA.

Kevin Kelly (K)

The Jackson Laboratory for Genomic Medicine, Farmington, CT, 06032, USA.

Greg Omerza (G)

The Jackson Laboratory for Genomic Medicine, Farmington, CT, 06032, USA.

Nicholas Renzette (N)

The Jackson Laboratory for Genomic Medicine, Farmington, CT, 06032, USA.

Anne E Watkins (AE)

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06510, USA.

Chaney C Kalinich (CC)

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06510, USA.

Tara Alpert (T)

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06510, USA.

Anderson F Brito (AF)

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06510, USA.

Rebecca Earnest (R)

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06510, USA.

Irina R Tikhonova (IR)

Yale Center for Genome Analysis, Yale University, New Haven, CT, 06510, USA.

Christopher Castaldi (C)

Yale Center for Genome Analysis, Yale University, New Haven, CT, 06510, USA.

John P Kelly (JP)

Wadsworth Center, New York State Department of Health, Albany, NY, 12208, USA.

Matthew Shudt (M)

Wadsworth Center, New York State Department of Health, Albany, NY, 12208, USA.

Jonathan Plitnick (J)

Wadsworth Center, New York State Department of Health, Albany, NY, 12208, USA.
Department of Biomedical Sciences, University at Albany, SUNY, Albany, NY, 12222, USA.

Erasmus Schneider (E)

Wadsworth Center, New York State Department of Health, Albany, NY, 12208, USA.
Department of Biomedical Sciences, University at Albany, SUNY, Albany, NY, 12222, USA.

Steven Murphy (S)

Murphy Medical Associates, Greenwich, CT, 06830, USA.

Caleb Neal (C)

Murphy Medical Associates, Greenwich, CT, 06830, USA.

Eva Laszlo (E)

Murphy Medical Associates, Greenwich, CT, 06830, USA.

Ahmad Altajar (A)

Murphy Medical Associates, Greenwich, CT, 06830, USA.

Claire Pearson (C)

Connecticut State Department of Public Health, Rocky Hill, CT, 06067, USA.

Anthony Muyombwe (A)

Connecticut State Department of Public Health, Rocky Hill, CT, 06067, USA.

Randy Downing (R)

Connecticut State Department of Public Health, Rocky Hill, CT, 06067, USA.

Jafar Razeq (J)

Connecticut State Department of Public Health, Rocky Hill, CT, 06067, USA.

Linda Niccolai (L)

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06510, USA.

Madeline S Wilson (MS)

Yale Health Center, Yale University, New Haven, CT, 06510, USA.

Margaret L Anderson (ML)

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06510, USA.

Jianhui Wang (J)

Department of Pathology, Yale University School of Medicine, New Haven, CT, 06510, USA.

Chen Liu (C)

Department of Pathology, Yale University School of Medicine, New Haven, CT, 06510, USA.

Pei Hui (P)

Department of Pathology, Yale University School of Medicine, New Haven, CT, 06510, USA.

Shrikant Mane (S)

Yale Center for Genome Analysis, Yale University, New Haven, CT, 06510, USA.

Bradford P Taylor (BP)

Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, 02115, USA.

William P Hanage (WP)

Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, 02115, USA.

Marie L Landry (ML)

Departments of Laboratory Medicine and Medicine, Yale University School of Medicine, New Haven, CT, 06510, USA.

David R Peaper (DR)

Departments of Laboratory Medicine and Medicine, Yale University School of Medicine, New Haven, CT, 06510, USA.

Kaya Bilguvar (K)

Yale Center for Genome Analysis, Yale University, New Haven, CT, 06510, USA.
Department of Genetics, Yale University School of Medicine, New Haven, CT, 06510, USA.

Joseph R Fauver (JR)

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06510, USA.

Chantal B F Vogels (CBF)

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06510, USA.

Lauren M Gardner (LM)

Department of Civil and Systems Engineering, Johns Hopkins University, Baltimore, 21218, MD, USA.

Virginia E Pitzer (VE)

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06510, USA.

Kirsten St George (K)

Wadsworth Center, New York State Department of Health, Albany, NY, 12208, USA.
Department of Biomedical Sciences, University at Albany, SUNY, Albany, NY, 12222, USA.

Mark D Adams (MD)

The Jackson Laboratory for Genomic Medicine, Farmington, CT, 06032, USA.

Nathan D Grubaugh (ND)

Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, 06510, USA. nathan.grubaugh@yale.edu.
Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT, 06510, USA. nathan.grubaugh@yale.edu.

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Classifications MeSH