Reversing Epithelial Polarity in Pluripotent Stem Cell-Derived Intestinal Organoids.
advanced 3D models
apicobasal polarity
epithelial organoids
intestinal organoids
reversed polarity
Journal
Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513
Informations de publication
Date de publication:
2022
2022
Historique:
received:
18
02
2022
accepted:
08
04
2022
entrez:
13
5
2022
pubmed:
14
5
2022
medline:
14
5
2022
Statut:
epublish
Résumé
The inner surface of the intestine is a dynamic system, composed of a single layer of polarized epithelial cells. The development of intestinal organoids was a major breakthrough since they robustly recapitulate intestinal architecture, regional specification and cell composition
Identifiants
pubmed: 35547177
doi: 10.3389/fbioe.2022.879024
pii: 879024
pmc: PMC9081652
doi:
Types de publication
Journal Article
Langues
eng
Pagination
879024Informations de copyright
Copyright © 2022 Kakni, López-Iglesias, Truckenmüller, Habibović and Giselbrecht.
Déclaration de conflit d'intérêts
RT and SG are founders and shareholders of 300MICRONS GmbH. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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