Residential greenness, asthma, and lung function among children at high risk of allergic sensitization: a prospective cohort study.
Allergy
Atopy
Child
Environment
Green space
Greenspace
Pediatric
Respiratory
Journal
Environmental health : a global access science source
ISSN: 1476-069X
Titre abrégé: Environ Health
Pays: England
ID NLM: 101147645
Informations de publication
Date de publication:
12 05 2022
12 05 2022
Historique:
received:
23
06
2021
accepted:
05
05
2022
entrez:
13
5
2022
pubmed:
14
5
2022
medline:
18
5
2022
Statut:
epublish
Résumé
While benefits of greenness to health have been reported, findings specific to child respiratory health are inconsistent. We utilized a prospective birth cohort followed from birth to age 7 years (n = 617). Residential surrounding greenness was quantified via Normalized Difference Vegetation Index (NDVI) within 200, 400, and 800 m distances from geocoded home addresses at birth, age 7 years, and across childhood. Respiratory health outcomes were assessed at age 7 years, including asthma and lung function [percent predicted forced expiratory volume in the first second (%FEV We noted evidence of positive confounding as inverse associations were attenuated upon adjustment in the multivariable models. We found evidence of effect measure modification of NDVI and asthma within 400 m at age 7 years by atopic status (p = 0.04), whereby children sensitized to common allergens were more likely to develop asthma as exposure to greenness increased (OR = 1.3, 95% CI: 0.9, 2.0) versus children not sensitized to common allergens (OR = 0.8, 95% CI: 0.5, 1.2). We found consistently positive associations between NDVI and %FEV Sensitivity to allergens may modify the effect of greenness on risk for asthma in children but greenness is likely beneficial for concurrent lung function regardless of allergic status.
Sections du résumé
BACKGROUND
While benefits of greenness to health have been reported, findings specific to child respiratory health are inconsistent.
METHODS
We utilized a prospective birth cohort followed from birth to age 7 years (n = 617). Residential surrounding greenness was quantified via Normalized Difference Vegetation Index (NDVI) within 200, 400, and 800 m distances from geocoded home addresses at birth, age 7 years, and across childhood. Respiratory health outcomes were assessed at age 7 years, including asthma and lung function [percent predicted forced expiratory volume in the first second (%FEV
RESULTS
We noted evidence of positive confounding as inverse associations were attenuated upon adjustment in the multivariable models. We found evidence of effect measure modification of NDVI and asthma within 400 m at age 7 years by atopic status (p = 0.04), whereby children sensitized to common allergens were more likely to develop asthma as exposure to greenness increased (OR = 1.3, 95% CI: 0.9, 2.0) versus children not sensitized to common allergens (OR = 0.8, 95% CI: 0.5, 1.2). We found consistently positive associations between NDVI and %FEV
CONCLUSION
Sensitivity to allergens may modify the effect of greenness on risk for asthma in children but greenness is likely beneficial for concurrent lung function regardless of allergic status.
Identifiants
pubmed: 35549707
doi: 10.1186/s12940-022-00864-w
pii: 10.1186/s12940-022-00864-w
pmc: PMC9097404
doi:
Substances chimiques
Allergens
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
52Informations de copyright
© 2022. The Author(s).
Références
Am J Public Health. 2010 Mar;100(3):540-6
pubmed: 19696386
Ann Allergy Asthma Immunol. 2019 Mar;122(3):289-295
pubmed: 30557617
Public Health Nurs. 2020 May;37(3):453-460
pubmed: 31899558
Int J Epidemiol. 2016 Dec 1;45(6):1887-1894
pubmed: 28089956
Environ Int. 2017 Mar;100:1-31
pubmed: 27881237
Environ Res. 2018 Feb;161:276-283
pubmed: 29172161
Environ Health. 2018 Dec 5;17(1):86
pubmed: 30518403
Eur Respir J. 2017 Jun 22;49(6):
pubmed: 28642307
Chest. 2007 Nov;132(5 Suppl):757S-769S
pubmed: 17998340
Pediatr Allergy Immunol. 2004 Oct;15(5):435-41
pubmed: 15482519
J Pediatr. 2006 Oct;149(4):505-11
pubmed: 17011322
Ann Epidemiol. 2019 Feb;30:37-43
pubmed: 30563729
Am J Respir Crit Care Med. 2001 Apr;163(5):1256-76
pubmed: 11316667
Nephrol Dial Transplant. 2015 Sep;30(9):1418-23
pubmed: 25324358
World Allergy Organ J. 2020 Jan 06;13(1):100096
pubmed: 32071664
Allergy. 2019 Oct;74(10):1977-1984
pubmed: 30934123
J Allergy Clin Immunol. 2014 Nov;134(5):993-9; discussion 1000
pubmed: 25439225
Environ Res. 2020 Dec;191:110132
pubmed: 32853665
Environ Health Perspect. 2013 Apr;121(4):494-500
pubmed: 23322788
J Epidemiol Community Health. 2008 Jul;62(7):647-9
pubmed: 18450765
Environ Int. 2020 Oct;143:105967
pubmed: 32702595
Sci Rep. 2019 Oct 22;9(1):15156
pubmed: 31641175
Annu Rev Public Health. 2014;35:207-28
pubmed: 24387090
Int J Hyg Environ Health. 2017 Apr;220(2 Pt B):494-502
pubmed: 28215483
Clin Exp Allergy. 2020 Oct;50(10):1176-1183
pubmed: 32662228
J Allergy Clin Immunol. 2005 Aug;116(2):279-84
pubmed: 16083780
J Pediatr. 2019 Apr;207:233-240
pubmed: 30545565
Int J Environ Res Public Health. 2017 Jun 23;14(7):
pubmed: 28644420
World Allergy Organ J. 2013 Jan 31;6(1):3
pubmed: 23663440
Am J Respir Crit Care Med. 2015 Aug 15;192(4):421-7
pubmed: 26106807
Environ Res. 2020 Jan;180:108869
pubmed: 31722804
Nat Plants. 2018 Jun;4(6):358-364
pubmed: 29735984
Allergy. 2019 Aug;74(8):1445-1456
pubmed: 30835837
Int J Environ Res Public Health. 2017 Feb 27;14(3):
pubmed: 28264461
J Expo Sci Environ Epidemiol. 2016 Jun;26(4):428-34
pubmed: 26956935
Eur Respir J. 2005 Aug;26(2):319-38
pubmed: 16055882
Int J Environ Res Public Health. 2018 Nov 13;15(11):
pubmed: 30428525
Sci Total Environ. 2019 Jun 10;668:760-767
pubmed: 30865906
Pediatr Pulmonol. 1993 Feb;15(2):75-88
pubmed: 8474788
Environ Health Perspect. 2007 Feb;115(2):278-84
pubmed: 17384778
Prev Med. 2006 Dec;43(6):437-41
pubmed: 16928396
J Environ Monit. 2003 Aug;5(4):557-62
pubmed: 12948227
Environ Health Perspect. 2014 Dec;122(12):1329-35
pubmed: 25157960
BMC Med Res Methodol. 2008 Oct 30;8:70
pubmed: 18973665
Am J Respir Crit Care Med. 2017 Mar 1;195(5):607-613
pubmed: 27606967
Respir Res. 2010 Jan 21;11:8
pubmed: 20092649
Int J Behav Nutr Phys Act. 2015 Feb 21;12:26
pubmed: 25886212
Curr Environ Health Rep. 2018 Mar;5(1):77-87
pubmed: 29392643
Environ Int. 2020 Jul;140:105749
pubmed: 32380303
Environ Res. 2021 Jul;198:110456
pubmed: 33188758
Environ Res. 2017 Nov;159:212-221
pubmed: 28803150
Environ Res. 2017 Oct;158:301-317
pubmed: 28672128
Allergy. 2015 Mar;70(3):245-56
pubmed: 25495759
Pediatrics. 2017 Apr;139(4):
pubmed: 28280210
BMJ Open. 2016 Apr 11;6(4):e010341
pubmed: 27067890
Am J Respir Crit Care Med. 2017 Jul 1;196(1):39-46
pubmed: 28146643