Impaired brain activity in patients with persistent atrial fibrillation assessed by near-infrared spectroscopy and its changes after catheter ablation.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
12 05 2022
12 05 2022
Historique:
received:
26
12
2021
accepted:
25
04
2022
entrez:
13
5
2022
pubmed:
14
5
2022
medline:
18
5
2022
Statut:
epublish
Résumé
Although the prevalence of cognitive impairment and depression is higher in patients with atrial fibrillation (AF) than in the general population, the mechanism has not been fully examined and impact of catheter ablation (CA) of AF also remains unclear. Recently, the development of near-infrared spectroscopy (NIRS) has enabled noninvasive measurements of regional cerebral blood volume and brain activity, in terms of cerebral oxyhemoglobin in the cerebral cortex. We assessed brain activities by NIRS, depressive symptoms by the Center for Epidemiologic Studies Depression Scale (CES-D) and cognitive function by Mini-Mental State Examination (MMSE). We then compared the results between AF patients (paroxysmal AF n = 18 and persistent AF n = 14) and control subjects (n = 29). Next, we also followed up persistent AF patients who kept sinus rhythm at 3 months after CA (n = 8) and measured their brain activities using NIRS, CES-D and MMSE after CA to investigate the associations of changes in brain activities with changes in both CES-D and MMSE. Our results showed that (1) frontal and temporal brain activities were lower in patients with persistent AF than both in control subjects and paroxysmal AF patients (P < 0.01), (2) frontal and temporal brain activities were improved in more than half of the persistent AF patients who kept sinus rhythm at 3 months after CA, especially in those who presented impaired brain activity before CA, and (3) improvement of frontal brain activity was associated with improvement of CES-D (R = - 0.793, P = 0.019), whereas improvement of temporal brain activity was associated with improvement of MMSE (R = 0.749, P = 0.033). NIRS measurement showed reduced frontal and temporal brain activities in the persistent AF patients, CA improved frontal and temporal brain activities in some of these patients, and associated with improvement of depressive state and/or improvement of cognitive function.
Identifiants
pubmed: 35550598
doi: 10.1038/s41598-022-12097-5
pii: 10.1038/s41598-022-12097-5
pmc: PMC9098845
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
7866Informations de copyright
© 2022. The Author(s).
Références
J Psychiatr Res. 1975 Nov;12(3):189-98
pubmed: 1202204
Front Psychiatry. 2021 Aug 13;12:704506
pubmed: 34475831
J Am Coll Cardiol. 2013 Aug 6;62(6):531-9
pubmed: 23684686
Heart Rhythm. 2012 Nov;9(11):1761-8
pubmed: 22863685
Clin Neuropsychol. 2007 Jan;21(1):9-37
pubmed: 17366276
Eur Heart J. 2016 Oct 7;37(38):2893-2962
pubmed: 27567408
J Cardiol. 2021 May;77(5):517-524
pubmed: 33248864
J Affect Disord. 2020 Jun 15;271:27-32
pubmed: 32312694
Neurology. 2011 Mar 8;76(10):914-22
pubmed: 21383328
Europace. 2018 Jul 1;20(7):1122-1128
pubmed: 28605437
Can J Cardiol. 2018 Jan;34(1):80-87
pubmed: 29275887
Neuroimage. 2002 Oct;17(2):719-31
pubmed: 12377147
JACC Clin Electrophysiol. 2018 Dec;4(12):1642-1643
pubmed: 30573132
J Cardiol. 2014 Oct;64(4):256-64
pubmed: 24674751
JAMA. 2007 Jul 18;298(3):324-9
pubmed: 17635893
J Anesth. 2019 Apr;33(2):167-196
pubmed: 30737572
Biol Psychiatry. 2004 Mar 1;55(5):501-11
pubmed: 15023578
Neuroimage. 2006 Nov 1;33(2):505-14
pubmed: 16945553
Resusc Plus. 2021 Mar 30;6:100109
pubmed: 34228034
Acta Neurol Scand. 1997 Nov;96(5):310-6
pubmed: 9405001
ESC Heart Fail. 2020 Oct;7(5):2508-2515
pubmed: 32558327
Int J Psychophysiol. 2010 Feb;75(2):77-85
pubmed: 19815035
J Am Coll Cardiol. 2013 Nov 19;62(21):1990-1997
pubmed: 23850917
Front Med (Lausanne). 2020 Oct 29;7:587930
pubmed: 33251235
Biol Psychiatry. 2002 Oct 1;52(7):679-93
pubmed: 12372658
Stroke. 1980 Jan-Feb;11(1):35-8
pubmed: 7355427
Clin Cardiol. 2011 May;34(5):327-31
pubmed: 21319172
Circ Arrhythm Electrophysiol. 2019 Jul;12(7):e007197
pubmed: 31442075
Anesth Analg. 2013 Mar;116(3):663-76
pubmed: 23267000
Sci Rep. 2018 Jan 10;8(1):402
pubmed: 29321655
Neuropsychiatr Dis Treat. 2014 Mar 25;10:507-11
pubmed: 24707175
Circ Arrhythm Electrophysiol. 2011 Oct;4(5):724-32
pubmed: 21747059
Front Psychiatry. 2021 Oct 01;12:716276
pubmed: 34658955
Am J Med. 2018 Dec;131(12):1408-1417
pubmed: 30076825
Neurology. 2012 Jan 31;78(5):326-33
pubmed: 22262748
J Am Heart Assoc. 2020 Feb 4;9(3):e014564
pubmed: 31973606
Neuroimage. 2014 Jan 15;85 Pt 1:498-507
pubmed: 23764293
J Cardiol. 2021 Feb;77(2):147-153
pubmed: 33371946
Psychol Med. 2002 Aug;32(6):1029-37
pubmed: 12214784
J Psychosom Res. 2007 Nov;63(5):509-13
pubmed: 17980224
J Neuroinflammation. 2013 Jun 28;10:78
pubmed: 23809138
Psychiatry Clin Neurosci. 2009 Aug;63(4):491-9
pubmed: 19496994
J Affect Disord. 2008 Feb;106(1-2):1-27
pubmed: 17707915
Europace. 2014 Jun;16(6):812-9
pubmed: 24351885
Circ Arrhythm Electrophysiol. 2020 Oct;13(10):e008602
pubmed: 32915644
Schizophr Res. 2008 Feb;99(1-3):250-62
pubmed: 18063344