The Relationship between Exposure to Airborne Particulate and DNA Adducts in Blood Cells in an Urban Population of Subjects with an Unhealthy Body Mass Index.


Journal

International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455

Informations de publication

Date de publication:
09 05 2022
Historique:
received: 21 03 2022
revised: 04 05 2022
accepted: 06 05 2022
entrez: 14 5 2022
pubmed: 15 5 2022
medline: 20 5 2022
Statut: epublish

Résumé

Bulky DNA adducts are a combined sign of aromatic chemical exposure, as well as an individual's ability to metabolically activate carcinogens and repair DNA damage. The present study aims to investigate the association between PM exposure and DNA adducts in blood cells, in a population of 196 adults with an unhealthy BMI (≥25). For each subject, a DNA sample was obtained for quantification of DNA adducts by sensitive

Identifiants

pubmed: 35565154
pii: ijerph19095761
doi: 10.3390/ijerph19095761
pmc: PMC9105958
pii:
doi:

Substances chimiques

DNA Adducts 0
Dust 0
Environmental Pollutants 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Alessandra Pulliero (A)

Department of Health Sciences, University of Genoa, 16132 Genoa, Italy.

Simona Iodice (S)

Epiget Lab, Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.

Angela Cecilia Pesatori (AC)

Epiget Lab, Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Luisella Vigna (L)

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

Zumama Khalid (Z)

Department of Health Sciences, University of Genoa, 16132 Genoa, Italy.

Valentina Bollati (V)

Epiget Lab, Department of Clinical Sciences and Community Health, University of Milan, 20122 Milan, Italy.

Alberto Izzotti (A)

Department of Experimental Medicine, University of Genoa, 16132 Genoa, Italy.
IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.

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Classifications MeSH