Anti-Inflammatory and Pro-Regenerative Effects of Hyaluronan-Chitlac Mixture in Human Dermal Fibroblasts: A Skin Ageing Perspective.

chitlac dermis extracellular matrix hyaluronan inflammation reactive oxygen species skin ageing

Journal

Polymers
ISSN: 2073-4360
Titre abrégé: Polymers (Basel)
Pays: Switzerland
ID NLM: 101545357

Informations de publication

Date de publication:
29 Apr 2022
Historique:
received: 31 03 2022
revised: 22 04 2022
accepted: 27 04 2022
entrez: 14 5 2022
pubmed: 15 5 2022
medline: 15 5 2022
Statut: epublish

Résumé

Inflammation and the accumulation of reactive oxygen species (ROS) play an important role in the structural and functional modifications leading to skin ageing. The reduction of inflammation, cellular oxidation and dermal extracellular matrix (ECM) alterations may prevent the ageing process. The aim of this study is to investigate the expression of pro-inflammatory markers and ECM molecules in human dermal fibroblasts derived from young and middle-aged women and the effects of lactose-modified chitosan (Chitlac

Identifiants

pubmed: 35566988
pii: polym14091817
doi: 10.3390/polym14091817
pmc: PMC9105413
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Alice Donato (A)

Histology Unit, Department of Molecular Medicine, University of Padova, 35121 Padova, Italy.

Elisa Belluzzi (E)

Musculoskeletal Pathology and Oncology Laboratory, Department of Surgery, Oncology and Gastroenterology (DiSCOG), University of Padova, 35128 Padova, Italy.
Orthopaedics and Orthopaedic Oncology, Department of Surgery, Oncology and Gastroenterology (DiSCOG), University of Padova, 35128 Padova, Italy.

Elena Mattiuzzo (E)

Histology Unit, Department of Molecular Medicine, University of Padova, 35121 Padova, Italy.

Rina Venerando (R)

Department of Molecular Medicine, University of Padova, 35121 Padova, Italy.

Massimiliano Cadamuro (M)

Department of Molecular Medicine, University of Padova, 35121 Padova, Italy.

Pietro Ruggieri (P)

Orthopaedics and Orthopaedic Oncology, Department of Surgery, Oncology and Gastroenterology (DiSCOG), University of Padova, 35128 Padova, Italy.

Vincenzo Vindigni (V)

Department of Neuroscience, University of Padova, 35100 Padova, Italy.

Paola Brun (P)

Histology Unit, Department of Molecular Medicine, University of Padova, 35121 Padova, Italy.

Classifications MeSH