Predictors of loss to follow-up among adult tuberculosis patients in Southern Ethiopia: a retrospective follow-up study.
Adults
Distance to health facility
Loss to follow-up
Southern Ethiopia
Tuberculosis
Journal
BMC public health
ISSN: 1471-2458
Titre abrégé: BMC Public Health
Pays: England
ID NLM: 100968562
Informations de publication
Date de publication:
14 05 2022
14 05 2022
Historique:
received:
22
08
2021
accepted:
09
05
2022
entrez:
15
5
2022
pubmed:
16
5
2022
medline:
18
5
2022
Statut:
epublish
Résumé
Loss to follow-up (LTFU) from tuberculosis (TB) treatment and care is a major public health problem as patients can be infectious and also may develop a multi-drug resistant TB (MDR-TB). The study aimed to assess whether LTFU differs by the distance TB patients travelled to receive care from the nearest health facility. A total of 402 patient cards of TB patients who received care were reviewed from March 1-30, 2020. The Kaplan-Meir curve with the Log-rank test was used to compare differences in LTFU by the distance travelled to reach to the nearest health facility for TB care. The Cox proportional hazard regression model was used to identify predictors. All statistical tests are declared significant at a p-value< 0.05. A total of 37 patients were LTFU with the incidence rate of 11.26 per 1000 person-months of observations (PMOs) (95% CI: 8.15-15.53). The incidence rate ratio was 12.19 (95% CI: 5.01-35.73) among the groups compared (those who travelled 10 km or more versus those who travelled less than 10 km). Age ≥ 45 years (aHR = 7.71, 95% CI: 1.72, 34.50), educational status (primary schooling, aHR = 3.54, 95% CI: 1.49, 8.40; secondary schooling, aHR = 2.75, 95% CI: 1.08, 7.03), lack of family support (aHR = 2.80, 95% CI: 1.27, 6.19), nutritional support (aHR = 3.40, 95% CI:1.68, 6.89), ≥ 10 km distance to travel to a health facility (aHR = 6.06, 95% CI: 2.33, 15.81) had significantly predicted LTFU from TB treatment and care. LTFU from adult TB care and treatment was 12 times higher among those who travelled ≥10 km to reach a health facility compared to those who travelled less. To retain adult TB patients in care and ensure appropriate treatment, health professionals and other stakeholders should give due attention to the factors that drive LTFU. We suggest identifying concerns of older patients at admission and those who travel long distance and establish social support platforms that could help people to complete TB treatment.
Sections du résumé
BACKGROUND
Loss to follow-up (LTFU) from tuberculosis (TB) treatment and care is a major public health problem as patients can be infectious and also may develop a multi-drug resistant TB (MDR-TB). The study aimed to assess whether LTFU differs by the distance TB patients travelled to receive care from the nearest health facility.
METHODS
A total of 402 patient cards of TB patients who received care were reviewed from March 1-30, 2020. The Kaplan-Meir curve with the Log-rank test was used to compare differences in LTFU by the distance travelled to reach to the nearest health facility for TB care. The Cox proportional hazard regression model was used to identify predictors. All statistical tests are declared significant at a p-value< 0.05.
RESULTS
A total of 37 patients were LTFU with the incidence rate of 11.26 per 1000 person-months of observations (PMOs) (95% CI: 8.15-15.53). The incidence rate ratio was 12.19 (95% CI: 5.01-35.73) among the groups compared (those who travelled 10 km or more versus those who travelled less than 10 km). Age ≥ 45 years (aHR = 7.71, 95% CI: 1.72, 34.50), educational status (primary schooling, aHR = 3.54, 95% CI: 1.49, 8.40; secondary schooling, aHR = 2.75, 95% CI: 1.08, 7.03), lack of family support (aHR = 2.80, 95% CI: 1.27, 6.19), nutritional support (aHR = 3.40, 95% CI:1.68, 6.89), ≥ 10 km distance to travel to a health facility (aHR = 6.06, 95% CI: 2.33, 15.81) had significantly predicted LTFU from TB treatment and care.
CONCLUSIONS
LTFU from adult TB care and treatment was 12 times higher among those who travelled ≥10 km to reach a health facility compared to those who travelled less. To retain adult TB patients in care and ensure appropriate treatment, health professionals and other stakeholders should give due attention to the factors that drive LTFU. We suggest identifying concerns of older patients at admission and those who travel long distance and establish social support platforms that could help people to complete TB treatment.
Identifiants
pubmed: 35568853
doi: 10.1186/s12889-022-13390-8
pii: 10.1186/s12889-022-13390-8
pmc: PMC9107690
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
976Informations de copyright
© 2022. The Author(s).
Références
BMC Infect Dis. 2019 May 28;19(1):474
pubmed: 31138129
Int J Tuberc Lung Dis. 2016 Sep;20(9):1205-11
pubmed: 27510247
BMC Infect Dis. 2016 Nov 8;16(1):653
pubmed: 27825309
Pathog Glob Health. 2015 Jul;109(5):221-7
pubmed: 26239760
Cad Saude Publica. 2018 May 10;34(5):e00048217
pubmed: 29768580
BMC Infect Dis. 2008 Jul 22;8:97
pubmed: 18647400
Emerg Infect Dis. 2016 Mar;22(3):491-502
pubmed: 26889786
ERJ Open Res. 2020 Mar 16;6(1):
pubmed: 32201689
PLoS One. 2018 Oct 18;13(10):e0205468
pubmed: 30335777
BMC Res Notes. 2017 Dec 4;10(1):680
pubmed: 29202880
PLoS One. 2019 Jun 17;14(6):e0218450
pubmed: 31206558
Pulmonology. 2019 May - Jun;25(3):190-192
pubmed: 31003958
Trop Med Health. 2020 Feb 18;48:9
pubmed: 32099523
J Tuberc Res. 2016 Dec;4(4):213-219
pubmed: 28042591
BMC Infect Dis. 2017 Aug 4;17(1):543
pubmed: 28778187
Lung India. 2009 Jan;26(1):9-16
pubmed: 20165588
Eur Respir J. 2019 Jan 10;53(1):
pubmed: 30630854
PLoS One. 2021 Mar 2;16(3):e0247945
pubmed: 33651842
Rev Salud Publica (Bogota). 2016 Sep-Oct;18(5):714-726
pubmed: 28453113
BMC Infect Dis. 2017 Mar 20;17(1):219
pubmed: 28320336
Int J Tuberc Lung Dis. 2018 Jun 1;22(6):649-654
pubmed: 29862949
J Clin Tuberc Other Mycobact Dis. 2018 Jul 03;12:41-47
pubmed: 31720398
Public Health Action. 2017 Mar 21;7(1):15-20
pubmed: 28775938
BMC Infect Dis. 2018 Mar 5;18(1):104
pubmed: 29506480
Public Health Action. 2017 Jun 21;7(2):127-133
pubmed: 28695086
PLoS Med. 2007 Feb;4(2):e37
pubmed: 17298164
BMC Public Health. 2010 Oct 28;10:651
pubmed: 21029405
J Epidemiol Glob Health. 2017 Dec;7(4):249-254
pubmed: 29110865