Catch-up vaccination campaign in children between 6 and 8 years old during COVID-19 pandemic: The experience in a COVID hub in Milan, Italy.


Journal

Vaccine
ISSN: 1873-2518
Titre abrégé: Vaccine
Pays: Netherlands
ID NLM: 8406899

Informations de publication

Date de publication:
09 06 2022
Historique:
received: 11 02 2022
revised: 03 04 2022
accepted: 04 05 2022
pubmed: 16 5 2022
medline: 7 6 2022
entrez: 15 5 2022
Statut: ppublish

Résumé

COVID-19 has led to disruption in routine immunization programs around the world. Effective strategies need to be developed to address the decline in vaccine coverage to avoid preventable disease outbreaks. Our study reports a 4-days campaign for the catching-up of missed vaccinations in children aged between 6 and 8 years, in Milan, Italy. The catch-up vaccination campaign (21st-24th of September 2021) involved children born in 2013, 2014 and 2015. These cohorts, if not already immunized, received the fourth dose of the Diphtheria-Tetanus-acellular Pertussis and Poliomyelitis vaccination (DTaPP4), the second dose of the Measles-Mumps and Rubella vaccination (MMR2) and Chickenpox, according to the Italian vaccine schedule. 3,943 letters were sent to children with a missing vaccination. 1,315 children, 33% of expected, were vaccinated during the campaign. The 2015 cohort was the one that benefited most from the initiative, 955 children were vaccinated for a total of 1,864 doses administered. This has led to a significant increase of 20.0 percentage points (p.p.) in vaccination coverages for the fourth dose of DTaPP and the second dose of MMR. 214 children for the 2014 cohort and 146 for the 2013 cohort were vaccinated during the following days, these cohorts have been already called previously therefore the participation in the campaign and consequently the increase in vaccination coverages were less substantial. This experience has demonstrated that a mass vaccination campaign could be a useful tool in catch-up strategies, even during the pandemic. It should be part of a bigger immunization program strategy that also includes efforts to simultaneously strengthen routine immunization services. With the appropriate organizational improvements, this initiative could pave the way for future successful campaigns involving different age groups and vaccinations.

Sections du résumé

BACKGROUND
COVID-19 has led to disruption in routine immunization programs around the world. Effective strategies need to be developed to address the decline in vaccine coverage to avoid preventable disease outbreaks. Our study reports a 4-days campaign for the catching-up of missed vaccinations in children aged between 6 and 8 years, in Milan, Italy.
METHODS
The catch-up vaccination campaign (21st-24th of September 2021) involved children born in 2013, 2014 and 2015. These cohorts, if not already immunized, received the fourth dose of the Diphtheria-Tetanus-acellular Pertussis and Poliomyelitis vaccination (DTaPP4), the second dose of the Measles-Mumps and Rubella vaccination (MMR2) and Chickenpox, according to the Italian vaccine schedule.
RESULTS
3,943 letters were sent to children with a missing vaccination. 1,315 children, 33% of expected, were vaccinated during the campaign. The 2015 cohort was the one that benefited most from the initiative, 955 children were vaccinated for a total of 1,864 doses administered. This has led to a significant increase of 20.0 percentage points (p.p.) in vaccination coverages for the fourth dose of DTaPP and the second dose of MMR. 214 children for the 2014 cohort and 146 for the 2013 cohort were vaccinated during the following days, these cohorts have been already called previously therefore the participation in the campaign and consequently the increase in vaccination coverages were less substantial.
CONCLUSIONS
This experience has demonstrated that a mass vaccination campaign could be a useful tool in catch-up strategies, even during the pandemic. It should be part of a bigger immunization program strategy that also includes efforts to simultaneously strengthen routine immunization services. With the appropriate organizational improvements, this initiative could pave the way for future successful campaigns involving different age groups and vaccinations.

Identifiants

pubmed: 35570078
pii: S0264-410X(22)00573-4
doi: 10.1016/j.vaccine.2022.05.005
pmc: PMC9098956
pii:
doi:

Substances chimiques

Diphtheria-Tetanus-acellular Pertussis Vaccines 0
Measles-Mumps-Rubella Vaccine 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3664-3669

Informations de copyright

Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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Auteurs

Matteo Mancarella (M)

Dept. Biomedical Sciences for Health, University of Milan, 20133 Milan, Italy. Electronic address: matteo.mancarella@unimi.it.

Federica Natarelli (F)

Dept. Biomedical Sciences for Health, University of Milan, 20133 Milan, Italy. Electronic address: federica.natarelli@unimi.it.

Caterina Bertolini (C)

Vaccination Unit, ASST Fatebenefratelli Sacco, 20157 Milan, Italy. Electronic address: caterina.bertolini@asst-fbf-sacco.it.

Antonino Zagari (A)

Direzione Socio-Sanitaria, ASST Fatebenefratelli-Sacco, 20157 Milan, Italy. Electronic address: antonino.zagari@asst-fbf-sacco.it.

Maria Enrica Bettinelli (M)

Dept. Biomedical Sciences for Health, University of Milan, 20133 Milan, Italy; Vaccination Unit, ASST Fatebenefratelli Sacco, 20157 Milan, Italy. Electronic address: maria.bettinelli@unimi.it.

Silvana Castaldi (S)

Dept. Biomedical Sciences for Health, University of Milan, 20133 Milan, Italy; IRCCS Fondazione Ca' Granda - Ospedale Maggiore Policlinico, 20122 Milan, Italy. Electronic address: silvana.castaldi@unimi.it.

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