A case of recalcitrant silicone granuloma treated with adalimumab: A case report.

Silicone granuloma adalimumab granulomatous inflammation recalcitrant silicone granuloma tumour necrosis factor-α inhibitor

Journal

SAGE open medical case reports
ISSN: 2050-313X
Titre abrégé: SAGE Open Med Case Rep
Pays: England
ID NLM: 101638686

Informations de publication

Date de publication:
2022
Historique:
entrez: 16 5 2022
pubmed: 17 5 2022
medline: 17 5 2022
Statut: epublish

Résumé

Liquid silicone is a relatively inexpensive injectable used for soft tissue augmentation. Injection of silicone is associated with a risk of delayed granuloma formation associated with elevated levels of tumour necrosis factor-α. We report a case of recalcitrant silicone granulomas following facial injections of silicone successfully treated with tumour necrosis factor-α blockade. Our case, as well as previous reports, demonstrates the effectiveness of this therapy for the treatment of foreign body granulomas from due to silicone.

Identifiants

pubmed: 35573102
doi: 10.1177/2050313X221093444
pii: 10.1177_2050313X221093444
pmc: PMC9102130
doi:

Types de publication

Case Reports

Langues

eng

Pagination

2050313X221093444

Informations de copyright

© The Author(s) 2022.

Déclaration de conflit d'intérêts

Declaration of conflicting interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Références

N Engl J Med. 2006 Jan 12;354(2):211-2
pubmed: 16407524
JAMA. 1975 Oct 20;234(3):308-9
pubmed: 1174244
Arch Dermatol. 2005 Jan;141(1):13-5
pubmed: 15655137
Dermatol Surg. 2021 Jun 1;47(6):849-851
pubmed: 32826602
Arch Dermatol. 1964 Dec;90:588-93
pubmed: 14206865
J Drugs Dermatol. 2006 Oct;5(9):894-6
pubmed: 17039657
J Dermatolog Treat. 2003 Dec;14(4):229-32
pubmed: 14660270
Dermatol Surg. 2001 Feb;27(2):198-200
pubmed: 11207699
JAAD Int. 2021 Apr 28;3:111-114
pubmed: 34409379
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Aug;108(2):237-41
pubmed: 19615662

Auteurs

Orli M Silverberg (OM)

Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

Benoit M Cyrenne (BM)

Division of Dermatology, Department of Medicine, University of Toronto, Toronto, ON, Canada.
Division of Dermatology, Women's College Hospital, Toronto, ON, Canada.

David Croitoru (D)

Division of Dermatology, Department of Medicine, University of Toronto, Toronto, ON, Canada.

Matthew K Sandre (MK)

Division of Dermatology, Department of Medicine, University of Toronto, Toronto, ON, Canada.

Kucy Pon (K)

Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Division of Dermatology, Department of Medicine, University of Toronto, Toronto, ON, Canada.
Division of Dermatology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.

Classifications MeSH