Immunotherapy-Induced Eosinophilic Tracheitis.
chronic cough
immunotherapy
melanoma
nivolumab-related adverse events
tracheitis
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Apr 2022
Apr 2022
Historique:
accepted:
12
04
2022
entrez:
16
5
2022
pubmed:
17
5
2022
medline:
17
5
2022
Statut:
epublish
Résumé
The present report describes the case of a 27-year-old male with a longstanding diagnosis of melanoma with metastatic disease treated with nivolumab, an immune checkpoint inhibitor. He presented with a chronic cough of unknown etiology, not responsive to standard of care treatment with cough suppressants. In view of this, a bronchoscopy was done, and biopsies were taken. The patient was diagnosed with eosinophilic tracheitis secondary to nivolumab. His symptoms improved with steroids and cessation of the immune checkpoint inhibitor. Prescribing physicians should be aware of these rare and potentially life-threatening toxic effects.
Identifiants
pubmed: 35573537
doi: 10.7759/cureus.24130
pmc: PMC9106536
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e24130Informations de copyright
Copyright © 2022, Tellez-Garcia et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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