Portal Vein Pulsatility Index as a Potential Risk of Venous Congestion Assessed by Magnetic Resonance Imaging: A Prospective Study on Healthy Volunteers.

fluid challenge fluid responsiveness magnetic resonance imaging portal vein pulsatility venous congestion

Journal

Frontiers in physiology
ISSN: 1664-042X
Titre abrégé: Front Physiol
Pays: Switzerland
ID NLM: 101549006

Informations de publication

Date de publication:
2022
Historique:
received: 08 11 2021
accepted: 18 03 2022
entrez: 16 5 2022
pubmed: 17 5 2022
medline: 17 5 2022
Statut: epublish

Résumé

High values of the portal vein pulsatility index (PI) have been associated with adverse outcomes in perioperative or critically ill patients. However, data on dynamic changes of PI related to fluid infusion are scarce. We aimed to determine if dynamic changes in PI are associated with the fluid challenge (FC). To address this challenge, we conducted a prospective single-center study. The population study included healthy subjects. FC consisted in the administration of 500 ml of Ringer lactate infusion over 5 min. The portal blood flow and PI were assessed by magnetic resonance imaging. The responsiveness to FC was defined as an increase in the cardiac stroke volume of at least 10% as assessed by echocardiography. We included 24 healthy volunteers. A total of fourteen (58%) subjects were responders, and 10 (42%) were non-responders. In the responder group, FC induced a significant increase in portal blood flow from 881 (762-1,001) at the baseline to 1,010 (778-1,106) ml min

Identifiants

pubmed: 35574483
doi: 10.3389/fphys.2022.811286
pii: 811286
pmc: PMC9101294
doi:

Types de publication

Journal Article

Langues

eng

Pagination

811286

Informations de copyright

Copyright © 2022 Abou-Arab, Beyls, Moussa, Huette, Beaudelot, Guilbart, De Broca, Yzet, Dupont, Bouzerar and Mahjoub.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Osama Abou-Arab (O)

Anesthesia and Critical Care Department, Amiens Hospital University, Amiens, France.

Christophe Beyls (C)

Anesthesia and Critical Care Department, Amiens Hospital University, Amiens, France.

Mouhamed Djahoum Moussa (MD)

CHU Lille, Pôle d'Anesthésie-Réanimation, Lille, France.

Pierre Huette (P)

Anesthesia and Critical Care Department, Amiens Hospital University, Amiens, France.

Elodie Beaudelot (E)

Anesthesia and Critical Care Department, Amiens Hospital University, Amiens, France.

Mathieu Guilbart (M)

Anesthesia and Critical Care Department, Amiens Hospital University, Amiens, France.

Bruno De Broca (B)

Anesthesia and Critical Care Department, Amiens Hospital University, Amiens, France.

Thierry Yzet (T)

Department of Radiology, Amiens Picardy University Hospital, Amiens, France.

Hervé Dupont (H)

Anesthesia and Critical Care Department, Amiens Hospital University, Amiens, France.

Roger Bouzerar (R)

Department of Biophysics and image processing, Amiens Picardy University Hospital, Amiens, France.

Yazine Mahjoub (Y)

Anesthesia and Critical Care Department, Amiens Hospital University, Amiens, France.

Classifications MeSH