Resistance training with or without nutritional supplementation showed no influence on muscle thickness in old-institutionalized adults: a secondary analysis of the Vienna Active Ageing Study.


Journal

European journal of physical and rehabilitation medicine
ISSN: 1973-9095
Titre abrégé: Eur J Phys Rehabil Med
Pays: Italy
ID NLM: 101465662

Informations de publication

Date de publication:
Aug 2022
Historique:
pubmed: 17 5 2022
medline: 30 7 2022
entrez: 16 5 2022
Statut: ppublish

Résumé

Resistance training and protein supplementation are recommended strategies to combat sarcopenia. Quantification of muscle thickness (MT) by musculoskeletal ultrasound is a promising method to follow changes in skeletal muscles. The aim of this study was to investigate the effect of six months of resistance training with or without nutritional supplementation on MT of M. quadriceps in institutionalized old adults. This is a prospective, randomized, multi-arm parallel and controlled intervention study. This study was conducted in five different retirement care facilities. Institutionalized individuals (mean age 82.6±6.2 years) were randomly assigned to an elastic band resistance training (N.=41), training with nutritional supplementation (N.=36) or control group (N.=40). Health status and handgrip strength were investigated at baseline. MT of all parts of M. quadriceps of the left leg was assessed using musculoskeletal ultrasound at baseline and after six months. Linear regression models adjusted for age, BMI and sex were calculated to investigate the influence of baseline characteristics on MT. Multivariable regression analyses were performed for investigation of study intervention on MT. Follow-up examinations were performed after 12 and 18 months. Handgrip strength of both hands was significantly correlated with MT of M. vastus lateralis. Moreover, the sum of regularly taken medication was significantly correlated to MT of all parts of quadriceps. Six months of training or nutritional supplementation was not able to alter MT. However, participants with lower baseline MT values or a higher number of diseases and medications at baseline showed significant higher increases in MT after intervention. Resistance training using elastic bands with or without nutritional supplementation did not alter MT of M. quadriceps of old institutionalized individuals. However, baseline values and health status had a significant influence on the training effect. As old individuals are very heterogenic according to their health and muscle status; further studies might focus on individualizing training regimes with particular emphasize on accompanied diseases and medications of this population.

Sections du résumé

BACKGROUND BACKGROUND
Resistance training and protein supplementation are recommended strategies to combat sarcopenia.
AIM OBJECTIVE
Quantification of muscle thickness (MT) by musculoskeletal ultrasound is a promising method to follow changes in skeletal muscles. The aim of this study was to investigate the effect of six months of resistance training with or without nutritional supplementation on MT of M. quadriceps in institutionalized old adults.
DESIGN METHODS
This is a prospective, randomized, multi-arm parallel and controlled intervention study.
SETTING METHODS
This study was conducted in five different retirement care facilities.
POPULATION METHODS
Institutionalized individuals (mean age 82.6±6.2 years) were randomly assigned to an elastic band resistance training (N.=41), training with nutritional supplementation (N.=36) or control group (N.=40).
METHODS METHODS
Health status and handgrip strength were investigated at baseline. MT of all parts of M. quadriceps of the left leg was assessed using musculoskeletal ultrasound at baseline and after six months. Linear regression models adjusted for age, BMI and sex were calculated to investigate the influence of baseline characteristics on MT. Multivariable regression analyses were performed for investigation of study intervention on MT. Follow-up examinations were performed after 12 and 18 months.
RESULTS RESULTS
Handgrip strength of both hands was significantly correlated with MT of M. vastus lateralis. Moreover, the sum of regularly taken medication was significantly correlated to MT of all parts of quadriceps. Six months of training or nutritional supplementation was not able to alter MT. However, participants with lower baseline MT values or a higher number of diseases and medications at baseline showed significant higher increases in MT after intervention.
CONCLUSIONS CONCLUSIONS
Resistance training using elastic bands with or without nutritional supplementation did not alter MT of M. quadriceps of old institutionalized individuals. However, baseline values and health status had a significant influence on the training effect.
CLINICAL REHABILITATION IMPACT CONCLUSIONS
As old individuals are very heterogenic according to their health and muscle status; further studies might focus on individualizing training regimes with particular emphasize on accompanied diseases and medications of this population.

Identifiants

pubmed: 35575453
pii: S1973-9087.22.06436-X
doi: 10.23736/S1973-9087.22.06436-X
pmc: PMC9980580
doi:

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Pagination

646-654

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Auteurs

Eva M Strasser (EM)

Institute for Physical Medicine and Rehabilitation, Klinik Favoriten, Wiener Gesundheitsverbund, Vienna, Austria - eva-maria.strasser@gesundheitsverbund.at.
Karl Landsteiner Institute for Remobilization and Functional Health, Vienna, Austria - eva-maria.strasser@gesundheitsverbund.at.

Bernhard Franzke (B)

Research Platform Active Ageing, University of Vienna, Vienna, Austria.
Department of Nutritional Sciences, Faculty of Life Sciences, University of Vienna, Vienna, Austria.

Marlene Hofmann (M)

Research Platform Active Ageing, University of Vienna, Vienna, Austria.
Center for Sport Science and University Sports, University of Vienna, Vienna, Austria.

Barbara Schober-Halper (B)

Research Platform Active Ageing, University of Vienna, Vienna, Austria.
Center for Sport Science and University Sports, University of Vienna, Vienna, Austria.

Stefan Oesen (S)

Research Platform Active Ageing, University of Vienna, Vienna, Austria.
Center for Sport Science and University Sports, University of Vienna, Vienna, Austria.

Waltraud Jandrasits (W)

Research Platform Active Ageing, University of Vienna, Vienna, Austria.
Department of Nutritional Sciences, Faculty of Life Sciences, University of Vienna, Vienna, Austria.

Alexandra Graf (A)

Section for Medical Statistics, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria.

Martin Ploder (M)

Klinik Donaustadt, Wiener Gesundheitsverbund, Vienna, Austria.

Norbert Bachl (N)

Research Platform Active Ageing, University of Vienna, Vienna, Austria.
Center for Sport Science and University Sports, University of Vienna, Vienna, Austria.

Michael Quittan (M)

Karl Landsteiner Institute for Remobilization and Functional Health, Vienna, Austria.

Karl-Heinz Wagner (KH)

Research Platform Active Ageing, University of Vienna, Vienna, Austria.
Department of Nutritional Sciences, Faculty of Life Sciences, University of Vienna, Vienna, Austria.

Barbara Wessner (B)

Research Platform Active Ageing, University of Vienna, Vienna, Austria.
Center for Sport Science and University Sports, University of Vienna, Vienna, Austria.

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Classifications MeSH