Active viral shedding in a vaccinated hospitalized patient infected with the delta variant (B.1.617.2) of SARS-CoV-2 and challenges of de-isolation.
COVID-19
Delta variant
Vaccine
Viral shedding
Journal
Journal of infection and public health
ISSN: 1876-035X
Titre abrégé: J Infect Public Health
Pays: England
ID NLM: 101487384
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
received:
26
02
2022
revised:
16
04
2022
accepted:
21
04
2022
medline:
23
10
2023
pubmed:
17
5
2022
entrez:
16
5
2022
Statut:
ppublish
Résumé
In the era of SARS-CoV-2 variants and COVID-19 vaccination, the duration of infectious viral shedding and isolation in post vaccine breakthrough infections is challenging and depends on disease severity. The current study described a case of SARS-CoV-2 Delta variant pneumonia requiring hospitalization. The patient received two doses of BNT162b2 COVID-19 vaccines, and he had positive SARS-CoV-2 viral cultures 12 days post symptom onset. The time between the second dose of vaccine and the breakthrough infection was 6 months. While immunosuppression is a known risk factor for prolonged infectious viral shedding, age and time between vaccination and breakthrough infection are important risk factors that warrant further studies.
Identifiants
pubmed: 35576779
pii: S1876-0341(22)00096-X
doi: 10.1016/j.jiph.2022.04.011
pmc: PMC9047479
pii:
doi:
Substances chimiques
BNT162 Vaccine
0
COVID-19 Vaccines
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
628-630Informations de copyright
Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Conflict of Interest None.