Predictive value of left atrial strain in relation to atrial fibrillation following acute myocardial infarction.


Journal

International journal of cardiology
ISSN: 1874-1754
Titre abrégé: Int J Cardiol
Pays: Netherlands
ID NLM: 8200291

Informations de publication

Date de publication:
01 10 2022
Historique:
received: 19 01 2022
revised: 04 04 2022
accepted: 11 05 2022
pubmed: 17 5 2022
medline: 10 8 2022
entrez: 16 5 2022
Statut: ppublish

Résumé

Atrial fibrillation (AF) is the most common arrythmia following ST-segment elevation myocardial infarction (STEMI) and can lead to stroke and other heart-related diseases. This study aimed to determine the prognostic value of left atrial (LA) strain, obtained by speckle tracking echocardiography (STE), in predicting incident AF outcomes following STEMI treated with primary percutaneous coronary intervention (pPCI). This prospective study comprised of 392 STEMI patients treated with pPCI. The patients had an echocardiography performed at a median of two days after their STEMI. Along with conventional measures, LA strain was obtained by speckle tracking from two apical projections. The outcome was new-onset atrial fibrillation. LA reservoir, contractile and conduit strain were measurable from echocardiograms of 303 included patients. At a median follow-up time of 5.6 years (IQR: 5.0-6.1 years), 18 patients (6,3%) developed incident AF. Mean age was 62.0 years ±11.5 and follow-up was 100%. Significantly lower LA strain values were observed in patients who experienced AF during follow-up as compared to patients who didn't. Both reservoir, contractile and conduit strain were significant univariable predictors. In the multivariable model, only LA reservoir strain remained a significant independent predictor of AF. Left atrial reservoir strain obtained by two-dimensional speckle tracking echocardiography is an independent predictor of incident AF following STEMI.

Sections du résumé

BACKGROUND
Atrial fibrillation (AF) is the most common arrythmia following ST-segment elevation myocardial infarction (STEMI) and can lead to stroke and other heart-related diseases. This study aimed to determine the prognostic value of left atrial (LA) strain, obtained by speckle tracking echocardiography (STE), in predicting incident AF outcomes following STEMI treated with primary percutaneous coronary intervention (pPCI).
METHODS AND RESULTS
This prospective study comprised of 392 STEMI patients treated with pPCI. The patients had an echocardiography performed at a median of two days after their STEMI. Along with conventional measures, LA strain was obtained by speckle tracking from two apical projections. The outcome was new-onset atrial fibrillation. LA reservoir, contractile and conduit strain were measurable from echocardiograms of 303 included patients. At a median follow-up time of 5.6 years (IQR: 5.0-6.1 years), 18 patients (6,3%) developed incident AF. Mean age was 62.0 years ±11.5 and follow-up was 100%. Significantly lower LA strain values were observed in patients who experienced AF during follow-up as compared to patients who didn't. Both reservoir, contractile and conduit strain were significant univariable predictors. In the multivariable model, only LA reservoir strain remained a significant independent predictor of AF.
CONCLUSION
Left atrial reservoir strain obtained by two-dimensional speckle tracking echocardiography is an independent predictor of incident AF following STEMI.

Identifiants

pubmed: 35577164
pii: S0167-5273(22)00736-7
doi: 10.1016/j.ijcard.2022.05.026
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

52-59

Informations de copyright

Copyright © 2022 The Author(s). Published by Elsevier B.V. All rights reserved.

Auteurs

Anne-Sophie Winther Svartstein (AW)

Department of Cardiology, Herlev and Gentofte University Hospital, Copenhagen, Denmark. Electronic address: svartstein@regionh.dk.

Mats Højbjerg Lassen (MH)

Department of Cardiology, Herlev and Gentofte University Hospital, Copenhagen, Denmark.

Kristoffer Grundtvig Skaarup (KG)

Department of Cardiology, Herlev and Gentofte University Hospital, Copenhagen, Denmark.

Gabriela Lladó Grove (GL)

Department of Cardiology, Herlev and Gentofte University Hospital, Copenhagen, Denmark.

Frederikke Vyff (F)

Department of Cardiology, Herlev and Gentofte University Hospital, Copenhagen, Denmark.

Kirstine Ravnkilde (K)

Department of Cardiology, Herlev and Gentofte University Hospital, Copenhagen, Denmark.

Sune Pedersen (S)

Department of Cardiology, Herlev and Gentofte University Hospital, Copenhagen, Denmark.

Søren Galatius (S)

Department of Cardiology, University Hospital Bispebjerg and Frederiksberg, Copenhagen, Denmark.

Daniel Modin (D)

Department of Cardiology, Herlev and Gentofte University Hospital, Copenhagen, Denmark.

Tor Biering-Sørensen (T)

Department of Cardiology, Herlev and Gentofte University Hospital, Copenhagen, Denmark; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH