Sirtuin modulators: past, present, and future perspectives.

Animals Gene Expression Regulation Mammals Neoplasms / drug therapy Protein Isoforms / metabolism Sirtuins
aging cancer drug discovery epigenetics metabolism neurodegeneration protein lysine deacylation sirtuin modulators sirtuins

Journal

Future medicinal chemistry
ISSN: 1756-8927
Titre abrégé: Future Med Chem
Pays: England
ID NLM: 101511162

Informations de publication

Date de publication:
06 2022
Historique:
pubmed: 19 5 2022
medline: 11 6 2022
entrez: 18 5 2022
Statut: ppublish

Résumé

Sirtuins are NAD

Identifiants

DOI: 10.4155/fmc-2022-0031 PMID: 35583203 PMC: PMC9185222
pubmed: 35583203
doi: 10.4155/fmc-2022-0031
pmc: PMC9185222
doi:

Substances chimiques

Protein Isoforms 0
Sirtuins EC 3.5.1.-

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

915-939

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM114306
Pays : United States

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Auteurs

Francesco Fiorentino (F)

Department of Drug Chemistry & Technologies, Sapienza University of Rome, P. le A. Moro 5, Rome, 00185, Italy.
ORCID: 0000-0003-3550-1860

Nicola Mautone (N)

Department of Drug Chemistry & Technologies, Sapienza University of Rome, P. le A. Moro 5, Rome, 00185, Italy.
ORCID: 0000-0002-2918-3184

Martina Menna (M)

Department of Drug Chemistry & Technologies, Sapienza University of Rome, P. le A. Moro 5, Rome, 00185, Italy.
ORCID: 0000-0001-5903-9135

Francesca D'Acunzo (F)

Institute of Biological Systems (ISB), Italian National Research Council (CNR), Sezione Meccanismi di Reazione, c/o Department of Chemistry, Sapienza University of Rome, P. le A. Moro 5, Rome, 00185, Italy.
ORCID: 0000-0001-8024-2402

Antonello Mai (A)

Department of Drug Chemistry & Technologies, Sapienza University of Rome, P. le A. Moro 5, Rome, 00185, Italy.
Pasteur Institute, Cenci-Bolognetti Foundation, Sapienza University of Rome, P. le A. Moro 5, Rome, 00185, Italy.
ORCID: 0000-0001-9176-2382

Dante Rotili (D)

Department of Drug Chemistry & Technologies, Sapienza University of Rome, P. le A. Moro 5, Rome, 00185, Italy.
ORCID: 0000-0002-8428-8763

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Sirtuin modulators: past, present, and future...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Sirtuin modulators: past, present, and future...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Sirtuin modulators: past, present, and future...
questionsmedicales.fr › Tumeurs › Sirtuin modulators: past, present, and future...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Isoformes de protéines › Sirtuin modulators: past, present, and future...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Sirtuines › Sirtuin modulators: past, present, and future...