Superwarfarin poisoning: challenges still remain.
Drugs and medicines
Exposures
Haematology (incl blood transfusion)
Poisoning
Journal
BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291
Informations de publication
Date de publication:
18 May 2022
18 May 2022
Historique:
pmc-release:
18
05
2024
entrez:
18
5
2022
pubmed:
19
5
2022
medline:
21
5
2022
Statut:
epublish
Résumé
Superwarfarin (long-acting anticoagulant rodenticide) poisoning should be suspected in unexplained bleeding with prolonged prothrombin time, especially in the absence of another explanation. Diagnosis and treatment of this intoxication remain a challenge as the direct analysis of superwarfarin in serum is not always possible. Therefore, toxin bioavailability remains unknown and close monitoring and treatment for long periods are required to avoid serious bleeding complications. Here, we discuss a case of suspected superwarfarin poisoning to highlight the challenges in early diagnosis and the challenges we encountered in treatment management and ensuring compliance for long periods.
Identifiants
pubmed: 35584857
pii: 15/5/e248385
doi: 10.1136/bcr-2021-248385
pmc: PMC9119149
pii:
doi:
Substances chimiques
4-Hydroxycoumarins
0
Anticoagulants
0
Rodenticides
0
bromfenacoum
A25P3CP5S7
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© BMJ Publishing Group Limited 2022. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.