Optically stimulated luminescence in state-of-the-art LYSO:Ce scintillators enables high spatial resolution 3D dose imaging.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
18 05 2022
Historique:
received: 21 01 2022
accepted: 06 05 2022
entrez: 18 5 2022
pubmed: 19 5 2022
medline: 21 5 2022
Statut: epublish

Résumé

In this contribution, we study the optically stimulated luminescence (OSL) exhibited by commercial [Formula: see text]:Ce crystals. This photon emission mechanism, complementary to scintillation, can trap a fraction of radiation energy deposited in the material and provides sufficient signal to develop a novel post-irradiation 3D dose readout. We characterize the OSL emission through spectrally and temporally resolved measurements and monitor the dose linearity response over a broad range. The measurements show that the [Formula: see text] centers responsible for scintillation also function as recombination centers for the OSL mechanism. The capture to OSL-active traps competes with scintillation originating from the direct non-radiative energy transfer to the luminescent centers. An OSL response on the order of 100 ph/MeV is estimated. We demonstrate the imaging capabilities provided by such an OSL photon yield using a proof-of-concept optical readout method. A 0.1 [Formula: see text] spatial resolution for doses as low as 0.5 Gy is projected using a cubic crystal to image volumetric dose profiles. While OSL degrades the intrinsic scintillating performance by reducing the number of scintillation photons emitted following the passage of ionizing radiation, it can encode highly resolved spatial information of the interaction point of the particle. This feature combines ionizing radiation spectroscopy and 3D reusable dose imaging in a single material.

Identifiants

pubmed: 35585168
doi: 10.1038/s41598-022-12255-9
pii: 10.1038/s41598-022-12255-9
pmc: PMC9117671
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

8301

Informations de copyright

© 2022. The Author(s).

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Auteurs

Mads L Jensen (ML)

Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, 8000, Aarhus, Denmark. mlj@phys.au.dk.

Jacob S Nyemann (JS)

Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, 8000, Aarhus, Denmark.

Ludvig P Muren (LP)

Danish Centre for Particle Therapy, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus, Denmark.
Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 82, 8200, Aarhus N, Denmark.

Brian Julsgaard (B)

Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, 8000, Aarhus, Denmark.

Peter Balling (P)

Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, 8000, Aarhus, Denmark.

Rosana M Turtos (RM)

Department of Physics and Astronomy, Aarhus University, Ny Munkegade 120, 8000, Aarhus, Denmark.

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Classifications MeSH