Application of Defined Approaches for Skin Sensitization to Agrochemical Products.

adverse outcome pathway agrochemicals alternatives to animal testing chemical allergy defined approaches new approach methodologies skin sensitization

Journal

Frontiers in toxicology
ISSN: 2673-3080
Titre abrégé: Front Toxicol
Pays: Switzerland
ID NLM: 101777990

Informations de publication

Date de publication:
2022
Historique:
received: 11 01 2022
accepted: 28 03 2022
entrez: 19 5 2022
pubmed: 20 5 2022
medline: 20 5 2022
Statut: epublish

Résumé

Skin sensitization testing is a regulatory requirement for safety evaluations of pesticides in multiple countries. Globally harmonized test guidelines that include

Identifiants

DOI: 10.3389/ftox.2022.852856 PMID: 35586187 PMC: PMC9108145
pubmed: 35586187
doi: 10.3389/ftox.2022.852856
pii: 852856
pmc: PMC9108145
doi:

Types de publication

Journal Article

Langues

eng

Pagination

852856

Informations de copyright

Copyright © 2022 Strickland, Truax, Corvaro, Settivari, Henriquez, McFadden, Gulledge, Johnson, Gehen, Germolec, Allen and Kleinstreuer.

Déclaration de conflit d'intérêts

DGA, JS, and JT are employed by Integrated Laboratory Systems, LLC. MC, RS, JH, JM, and SG are employed by Dow Agrosciences (member of Corteva Agriscience group of companies). VJ is employed by Burleson Research Technologies, Inc. TG was employed by Burleson Research Technologies, Inc., at the time of the h-CLAT work and is now employed by StrideBio, Inc. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Judy Strickland (J)

Integrated Laboratory Systems, LLC, Research Triangle Park, NC, United States.

James Truax (J)

Integrated Laboratory Systems, LLC, Research Triangle Park, NC, United States.

Marco Corvaro (M)

Corteva Agriscience, Regulatory Sciences R&D, Rome, Italy.

Raja Settivari (R)

Corteva Agriscience, General, Genetic, and Molecular Toxicology, Newark, DE, United States.

Joseph Henriquez (J)

Corteva Agriscience, Regulatory Toxicology and Risk Group, Indianapolis, IN, United States.

Jeremy McFadden (J)

Corteva Agriscience, Regulatory Toxicology and Risk Group, Indianapolis, IN, United States.

Travis Gulledge (T)

Burleson Research Technologies, Inc., Morrisville, NC, United States.

Victor Johnson (V)

Burleson Research Technologies, Inc., Morrisville, NC, United States.

Sean Gehen (S)

Corteva Agriscience, Regulatory Toxicology and Risk Group, Indianapolis, IN, United States.

Dori Germolec (D)

Systems Toxicology Branch, Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States.
National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States.

David G Allen (DG)

Integrated Laboratory Systems, LLC, Research Triangle Park, NC, United States.

Nicole Kleinstreuer (N)

National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods, Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States.

Classifications MeSH