Single-nucleotide polymorphisms in the sulfatase-modifying factor 1 gene are associated with lung function and COPD.


Journal

ERJ open research
ISSN: 2312-0541
Titre abrégé: ERJ Open Res
Pays: England
ID NLM: 101671641

Informations de publication

Date de publication:
Apr 2022
Historique:
received: 04 12 2021
accepted: 17 02 2022
entrez: 19 5 2022
pubmed: 20 5 2022
medline: 20 5 2022
Statut: epublish

Résumé

Single nucleotide polymorphisms (SNPs) in various genes have been shown to associate with COPD, suggesting a role in disease pathogenesis. Sulfatase modifying factor (SUMF1) is a key modifier in connective tissue remodelling, and we have shown previously that several SNPs in

Identifiants

pubmed: 35586453
doi: 10.1183/23120541.00668-2021
pii: 00668-2021
pmc: PMC9108960
pii:
doi:

Types de publication

Journal Article

Langues

eng

Informations de copyright

Copyright ©The authors 2022.

Déclaration de conflit d'intérêts

Conflict of interest: P. Wollmer reports receiving support for the present manuscript from the Swedish Heart and Lung Foundation; payment or honoraria for lectures, presentations, speaker bureaus, manuscript writing or educational events from Chiesi Pharma, outside the submitted work: and a patent issued for a device and method for pulmonary function measurement (no licence). The remaining authors have nothing to disclose.

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Auteurs

Linnea Jarenbäck (L)

Dept of Clinical Sciences Lund, Respiratory Medicine and Allergology, Lund University, Lund, Sweden.

Sophia Frantz (S)

Dept of Translational Science, Clinical Physiology, Lund University, Skåne University Hospital, Malmö, Sweden.

Julie Weidner (J)

Dept of Clinical Sciences Lund, Respiratory Medicine and Allergology, Lund University, Lund, Sweden.

Jaro Ankerst (J)

Dept of Clinical Sciences Lund, Respiratory Medicine and Allergology, Lund University, Lund, Sweden.

Ulf Nihlén (U)

Dept of Clinical Sciences Lund, Respiratory Medicine and Allergology, Lund University, Lund, Sweden.

Leif Bjermer (L)

Dept of Clinical Sciences Lund, Respiratory Medicine and Allergology, Lund University, Lund, Sweden.

Per Wollmer (P)

Dept of Translational Science, Clinical Physiology, Lund University, Skåne University Hospital, Malmö, Sweden.

Ellen Tufvesson (E)

Dept of Clinical Sciences Lund, Respiratory Medicine and Allergology, Lund University, Lund, Sweden.

Classifications MeSH