Laser coagulation and hemostasis of large diameter blood vessels: effect of shear stress and flow velocity.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
19 05 2022
19 05 2022
Historique:
received:
24
10
2021
accepted:
29
04
2022
entrez:
19
5
2022
pubmed:
20
5
2022
medline:
24
5
2022
Statut:
epublish
Résumé
Photocoagulation of blood vessels offers unambiguous advantages to current radiofrequency approaches considering the high specificity of blood absorption at available laser wavelengths (e.g., 532 nm and 1.064 µm). Successful treatment of pediatric vascular lesions, such as port-wine stains requiring microvascular hemostasis, has been documented. Although laser treatments have been successful in smaller diameter blood vessels, photocoagulation of larger sized vessels is less effective. The hypothesis for this study is that a primary limitation in laser coagulation of large diameter blood vessels (500-1000 µm) originates from shear stress gradients associated with higher flow velocities along with temperature-dependent viscosity changes. Laser (1.07 µm) coagulation of blood vessels was tested in the chicken chorio-allantoic membrane (CAM). A finite element model is developed that includes hypothetical limitations in laser coagulation during irradiation. A protocol to specify laser dosimetry is derived from OCT imaging and angiography observations as well as finite element model results. Laser dosimetry is applied in the CAM model to test the experimental hypothesis that blood shear stress and flow velocity are important parameters for laser coagulation and hemostasis of large diameter blood vessels (500-1000 µm). Our experimental results suggest that shear stress and flow velocity are fundamental in the coagulation of large diameter blood vessels (500-1000 µm). Laser dosimetry is proposed and demonstrated for successful coagulation and hemostasis of large diameter CAM blood vessels.
Identifiants
pubmed: 35589781
doi: 10.1038/s41598-022-12128-1
pii: 10.1038/s41598-022-12128-1
pmc: PMC9120470
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
8375Informations de copyright
© 2022. The Author(s).
Références
Anderson, R. R. & Parrish, J. A. Microvasculature can be selectively damaged using dye lasers: A basic theory and experimental evidence in human skin. Lasers Surg. Med. 1, 263–276 (1981).
doi: 10.1002/lsm.1900010310
Lanigan, S. W. & Taibjee, S. M. Recent advances in laser treatment of port-wine stains. Br. J. Dermatol. https://doi.org/10.1111/j.1365-2133.2004.06163.x (2004).
doi: 10.1111/j.1365-2133.2004.06163.x
pubmed: 15377336
Tunnell, J. W. et al. Effects of cryogen spray cooling and high radiant exposures on selective vascular injury during laser irradiation of human skin. Arch. Dermatol. 139, 743 (2003).
pubmed: 12810505
doi: 10.1001/archderm.139.6.743
Barton, J. K. et al. Photothermal coagulation of blood vessels : A comparison of high-speed optical coherence tomography and numerical modelling. Phys. Med. Biol. 46, 1665–1678 (2001).
pubmed: 11419626
doi: 10.1088/0031-9155/46/6/306
Kimel, S. et al. Differential Vascular Response to Laser Photothermolysis. J. Invest. Dermatol. 103, 693–700 (1994).
pubmed: 7963659
doi: 10.1111/1523-1747.ep12398548
Anderson, R. R., Jaenicke, K. F. & Parrish, J. A. Mechanisms of selective vascular changes caused by dye lasers. Lasers Surg. Med. 3, 211–215 (1983).
pubmed: 6668976
doi: 10.1002/lsm.1900030303
Garden, J. M., Polla, L. L. & Tan, O. T. The treatment of port-wine stains by the pulsed dye laser: Analysis of pulse duration and long-term therapy. Arch. Dermatol. 124, 889–896 (1988).
pubmed: 3377518
doi: 10.1001/archderm.1988.01670060035012
Pratt, A. G. Birthmarks in infants. AMA. Arch. Derm. Syphilol. 67, 302–305 (1953).
pubmed: 13029926
doi: 10.1001/archderm.1953.01540030065006
Lanigan, S. W., Cotterill, J. A. Port wine stains and treatment. Bioengineering of the Skin: Cutaneous Blood Flow and Erythema 2, 183 (1994).
Burton, B. K., Schulz, C. J., Angle, B. & Burd, L. I. An increased incidence of haemangiomas in infants born following chorionic villus sampling (CVS). Prenat. Diagn. 15, 209–214 (1995).
pubmed: 7784377
doi: 10.1002/pd.1970150302
Iacopino, D. G. Hemostasis in brain tumor surgery using the Aquamantys system. Med. Sci. Monit. 20, 538–543 (2014).
pubmed: 24686845
pmcid: 3981681
doi: 10.12659/MSM.890583
Hammond, J. S., Muirhead, W., Zaitoun, A. M., Cameron, I. C. & Lobo, D. N. Comparison of liver parenchymal ablation and tissue necrosis in a cadaveric bovine model using the Harmonic Scalpel™, the LigaSure™, the Cavitron Ultrasonic Surgical Aspirator® and the Aquamantys ® devices. HPB 14, 828–832 (2012).
doi: 10.1111/j.1477-2574.2012.00547.x
Yoshida, S. et al. A morphological study of the blood vessels associated with periodontal probing depth in human gingival tissue. Okajimas Folia Anatomica Japonica 88, 103–109 (2011).
pubmed: 22519069
doi: 10.2535/ofaj.88.103
Romanos, G. E. Diode laser soft-tissue surgery: Advancements aimed at consistent cutting, improved clinical outcomes. Compend. Contin. Educ. Dent. 34, 752–7 (2013).
pubmed: 24571504
Vitruk, P. & Levine, R. Hemostasis and coagulation with ablative soft-tissue dental lasers and hot-tip devices. Insid. Dent. 12, 1–4 (2016).
Halak, F. et al. Immediate laser-induced hemostasis in anticoagulated rats subjected to oral soft tissue surgery: A double-blind study. Braz. Oral Res. 32, 1–8 (2018).
Hale, G. M. & Querry, M. R. Optical constants of water in the 200-nm to 200-μm wavelength region. Appl. Opt. 12, 555 (1973).
pubmed: 20125343
doi: 10.1364/AO.12.000555
Jacques, S. L. Optical properties of biological tissues: A review. Phys. Med. Biol. 58, 37–61 (2013).
doi: 10.1088/0031-9155/58/11/R37
Giglio, N. C. & Fried, N. M. Computational simulations for infrared laser sealing and cutting of blood vessels. IEEE J. Sel. Top. Quantum Electron Publ. IEEE Lasers Electro Opt. Soc. 27, 1–8 (2021).
doi: 10.1109/JSTQE.2020.3045912
Giglio, N. C. et al. Rapid sealing and cutting of porcine blood vessels, ex vivo, using a high-power, 1470-nm diode laser. J. Biomed. Opt. 19, 38002 (2014).
pubmed: 24658792
doi: 10.1117/1.JBO.19.3.038002
Katta, N. et al. Laser brain cancer surgery in a xenograft model guided by optical coherence tomography. Theranostics 9, 3555–3564 (2019).
pubmed: 31281497
pmcid: 6587169
doi: 10.7150/thno.31811
Katta, N., Estrada, A. D., McErloy, A. B. & Milner, T. E. Fiber-laser platform for precision brain surgery. Biomed. Opt. Express 13, 1985–1994 (2022).
pubmed: 35519278
pmcid: 9045916
doi: 10.1364/BOE.449312
Katta, N., McElroy, A. B., Estrada, A. D. & Milner, T. E. Optical coherence tomography image-guided smart laser knife for surgery. Lasers Surg. Med. 50, 202–212 (2017).
pubmed: 28782115
doi: 10.1002/lsm.22705
Nelson, J. S., Kelly, K. M., Zhao, Y. & Chen, Z. Imaging blood flow in human port-wine stain in situ and in real time using optical doppler tomography. Arch. Dermatol. 137, 741 (2001).
pubmed: 11405763
Tunnell, J. W. Selective vascular injury during cutaneous laser therapy. Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society, Engineering in Medicine and Biology (2002).
Barsky, S. H., Rosen, S., Geer, D. E. & Noe, J. M. The nature and evolution of port wine stains: A computer-assisted study. J. Invest. Dermatol. 74, 154–157 (1980).
pubmed: 7359006
doi: 10.1111/1523-1747.ep12535052
Kaufmann, R. & Hibst, R. Pulsed erbium:YAG laser ablation in cutaneous surgery. Lasers Surg. Med. 19, 324–330 (1996).
pubmed: 8923427
doi: 10.1002/(SICI)1096-9101(1996)19:3<324::AID-LSM7>3.0.CO;2-U
Vogel, A. & Venugopalan, V. Mechanisms of pulsed laser ablation of biological tissues. Chem. Rev. 103, 577 (2003).
pubmed: 12580643
doi: 10.1021/cr010379n
Tawaza, H. Measurement of respiratory parameters in blood of chicken embryo. J. Appl. Physiol. 30, 17 (1971).
doi: 10.1152/jappl.1971.30.1.17
Segura, P. N. T. The chicken chorioallantoic membrane model in biology, medicine and bioengineering the chicken chorioallantoic membrane model in biology, medicine and bioengineering. Angiogenesis https://doi.org/10.1007/s10456-014-9440-7 (2014).
doi: 10.1007/s10456-014-9440-7
pubmed: 25138280
pmcid: 4583126
Honda, N. et al. Optical properties of tumor tissues grown on the chorioallantoic membrane of chicken eggs : tumor model to assay of tumor response to photodynamic therapy. J. Biomed. Opt. 20, 125001 (2015).
pubmed: 26662299
doi: 10.1117/1.JBO.20.12.125001
Nadort, A., Kalk, K., Van Leeuwen, T. G. & Faber, D. J. Quantitative blood flow velocity imaging using laser speckle flowmetry. Sci. Rep. https://doi.org/10.1038/srep25258 (2016).
doi: 10.1038/srep25258
pubmed: 27126250
pmcid: 4850477
Lecomte, B. Y. P., Nooy, D. U. & York, N. The viscosity of blood serum as a function of temperature. J. Gen. Physiol. 12(3), 363–377 (1929).
doi: 10.1085/jgp.12.3.363
Babilas, P., Schreml, S., Eames, T. & Hohenleutner, U. Split-face comparison of intense pulsed light with short- and long-pulsed dye lasers for the treatment of port-wine stains. Lasers Surg. Med. 727, 720–727 (2010).
doi: 10.1002/lsm.20964
Date, P. Confocal microscopy study of nerves and blood vessels in untreated and treated port wine stains : Preliminary observations. Dermatol. Surg. https://doi.org/10.1111/j.1524-4725.2004.30259.x (2004).
doi: 10.1111/j.1524-4725.2004.30259.x
Drosner, M., Stockmeier, M., Gatty, F. & Hellbru, G. Comparison of intense pulsed light ( IPL ) and pulsed dye laser (PDL ) in port-wine stain treatment. Med. Laser Appl. 23, 133–140 (2008).
doi: 10.1016/j.mla.2008.05.004
Parlette, E. C. et al. Optimal pulse durations for the treatment of leg telangiectasias with a neodymium YAG Laser. Lasers Surg. Med. Off. J. Am. Soc. Laser Med. Surg. 105, 98–105 (2006).
Wallwiener, C. W. et al. Bipolar vessel sealing : Instrument contamination and wear have little effect on seal quality and success in a porcine in vitro model. Langenbeck’s Arch. Surg. https://doi.org/10.1007/s00423-014-1234-2 (2014).
doi: 10.1007/s00423-014-1234-2
Ikami, T. M., Anibuchi, M. W. & Ikuni, N. M. Bumping phenomenon during continuous coagulation with bipolar forceps. Neurologia Medico-Chirurgica 52, 731–735 (2012).
doi: 10.2176/nmc.52.731
Kimel, S., Svaasand, L. O., Cao, D., Hammer-Wilson, M. J. & Nelson, J. S. Vascular response to laser photothermolysis as a function of pulse duration, vessel type, and diameter: Implications for port wine stain laser therapy. Lasers Surg. Med. 30, 160–169 (2002).
pubmed: 11870797
doi: 10.1002/lsm.10016
Murphy, M. J. & Torstensson, P. A. Thermal relaxation times : An outdated concept in photothermal treatments. Lasers Med. Sci. https://doi.org/10.1007/s10103-013-1445-8 (2014).
doi: 10.1007/s10103-013-1445-8
pubmed: 24584904
Lanigan, S. W. Port-wine stains unresponsive to pulsed dye laser : Explanations and solutions. Br. J. Dermatol. 139, 173–177 (1998).
pubmed: 9767228
doi: 10.1046/j.1365-2133.1998.02351.x
Maibier, M. et al. Structure and hemodynamics of vascular networks in the chorioallantoic membrane of the chicken. Am. J. Physiol. Hear. Circ. Physiol. https://doi.org/10.1152/ajpheart.00786.2015 (2016).
doi: 10.1152/ajpheart.00786.2015
Tunnell, J. W., Wang, L. V. & Anvari, B. Optimum pulse duration and radiant exposure for vascular laser therapy of dark port-wine skin : A theoretical study. Appl. Opt. 42, 1367–1378 (2003).
pubmed: 12638894
doi: 10.1364/AO.42.001367
Barozzi, G. S. & Dumas, A. Convective heat transfer coefficients in the circulation. J. Biomech. Eng. 113, 308 (2008).
doi: 10.1115/1.2894889
Consiglieri, L., dos Santos, I. & Haemmerich, D. Theoretical analysis of the heat convection coefficient in large vessels and the significance for thermal ablative therapies. Phys. Med. Biol. 48, 4125–4134 (2003).
pubmed: 14727756
doi: 10.1088/0031-9155/48/24/010
Black, J. F. & Barton, J. K. Chemical and structural changes in blood undergoing laser photocoagulation. Photochem. Photobiol. 80, 89–97 (2004).
pubmed: 15339203
doi: 10.1562/2004-03-05-RA-102.1
Black, J. F., Wade, N. & Barton, J. K. Mechanistic comparison of blood undergoing laser photocoagulation at 532 and 1, 064 nm. Lasers Surg. Med. Off. J. Am. Soc. Laser Med. Surg. 165, 155–165 (2005).
Kimel, S. et al. Differential vascular response to laser photothermolysis. J. Investig. Dermatol. https://doi.org/10.1111/1523-1747.ep12398548 (1994).
doi: 10.1111/1523-1747.ep12398548
pubmed: 7963659
Tryggvason, G. et al. A front-tracking method for the computations of multiphase flow. J. Comput. Phys. 759, 708–759 (2001).
doi: 10.1006/jcph.2001.6726
Harold, K. L. et al. Comparison of ultrasonic energy, bipolar thermal energy, and vascular clips for the hemostasis of small-, medium-, and large-sized arteries. Surg. Endosc. Other Interv. Tech. 17, 1228–1230 (2003).
Chastagner, M. W., Miller, S. F., Shih, A. J. & Geiger, J. D. Vessel sealing using the bipolar electrosurgical method. In International Manufacturing Science and Engineering Conference 673–680 (2009). https://doi.org/10.1115/msec2007-31166 .
Anderson, R. R. et al. Selective photothermolysis of cutaneous pigmentation by Q-switched Nd: YAG laser pulses at 1064, 532 and 355 nm. J. Invest. Dermatol. 93, 28–32 (2004).
doi: 10.1111/1523-1747.ep12277339
Friebel, M. Determination of optical properties of human blood in the spectral range 250 to 1100 nm using Monte Carlo simulations with hematocrit-dependent effective. J. Biomed. Opt. 11, 1–10 (2006).
Friebel, M. Influence of oxygen saturation on the optical scattering properties of human red blood cells in the spectral range 250 to 2000 nm. J. Biomed. Opt. 14, 1–6 (2009).
doi: 10.1117/1.3127200
Meinke, M., Müller, G., Helfmann, J. & Friebel, M. Empirical model functions to calculate hematocrit-dependent optical properties of human blood. Appl. Opt. 46, 1742 (2007).
pubmed: 17356617
doi: 10.1364/AO.46.001742
Chae, Y., Aguilar, G., Lavernia, E. J. & Wong, B. J. F. Characterization of temperature dependent mechanical behavior of cartilage. Charact. Temp. Depend. Mech. Behav. Cartil. 278, 271–278 (2003).
Shafirstein, G., Buckmiller, L. M. & Waner, M. Mathematical modeling of selective photothermolysis to aid the treatment of vascular malformations and hemangioma with pulsed dye laser. Lasers Med. Sci. 22, 111–118. https://doi.org/10.1007/s10103-006-0427-5 (2007).
doi: 10.1007/s10103-006-0427-5
pubmed: 17268765
Dai, T., Pikkula, B. M., Tunnell, J. W., Chang, D. W. & Anvari, B. Thermal response of human skin epidermis to 595-nm laser irradiation at high incident dosages and long pulse durations in conjunction with cryogen spray cooling : An ex-vivo study. Lasers Surg. Med. Off. J. Am. Soc. Laser Med. Surg. 24, 16–24 (2003).