The role of the amygdala in processing social and affective touch.
Journal
Current opinion in behavioral sciences
ISSN: 2352-1546
Titre abrégé: Curr Opin Behav Sci
Pays: Netherlands
ID NLM: 101644944
Informations de publication
Date de publication:
Feb 2022
Feb 2022
Historique:
entrez:
23
5
2022
pubmed:
24
5
2022
medline:
24
5
2022
Statut:
ppublish
Résumé
The amygdala plays a central role in emotion and social behavior, yet its role in processing social and affective touch is not well established. Longitudinal studies reveal that touch-deprived infants show later in life exaggerated emotional reactivity related to structural and functional changes in the amygdala and other brain structures. The internal organization and connectivity of the amygdala is well-suited to process the sensory features of tactile stimuli and also the socio-cognitive dimensions of the received touch. The convergent processing of bottom-up and top-down pathways that carry information about touch results in the elaboration of context appropriate autonomic responses. Indeed, the positive value of affective touch in humans and social grooming in non-human primates is correlated with vagal tone and the release of oxytocin and endogenous opioids. Grooming, the non-human primate equivalent of affective touch in humans, reduces vigilance, that depends on the amygdala. During touch-induced vagal tone and low vigilance, neural activity in the amygdala is substantially different from activity corresponding to the attentive processing of tactile stimuli. Under these circumstances neurons no longer respond phasically to each touch stimulus, rather they signal a sustained functional state in which the amygdala appears decoupled from monitoring the external environment.
Identifiants
pubmed: 35602667
doi: 10.1016/j.cobeha.2021.08.004
pmc: PMC9119433
mid: NIHMS1805486
doi:
Types de publication
Journal Article
Langues
eng
Pagination
46-53Subventions
Organisme : NIMH NIH HHS
ID : R01 MH121009
Pays : United States
Déclaration de conflit d'intérêts
Conflict of interest statement Nothing declared.
Références
Curr Opin Neurobiol. 2010 Apr;20(2):221-30
pubmed: 20299204
Sci Rep. 2015 May 21;5:10499
pubmed: 25994551
Front Behav Neurosci. 2015 Sep 24;9:243
pubmed: 26441573
Prog Neurobiol. 1998 Jun;55(3):257-332
pubmed: 9643556
Anim Behav. 2000 Apr;59(4):763-770
pubmed: 10792931
MAGMA. 2008 Jul;21(4):279-90
pubmed: 18661163
Am J Physiol. 1995 Mar;268(3 Pt 2):R666-75
pubmed: 7900909
eNeuro. 2019 Oct 14;6(5):
pubmed: 31533960
Neuroimage. 2016 Sep;138:242-247
pubmed: 27238727
Soc Neurosci. 2021 Feb;16(1):92-102
pubmed: 31810428
J Neurosci. 2013 Jun 19;33(25):10503-11
pubmed: 23785162
Physiol Behav. 1989 Mar;45(3):667-70
pubmed: 2756061
R Soc Open Sci. 2021 Sep 8;8(9):210287
pubmed: 34527270
J Comp Neurol. 2005 Jun 13;486(4):295-317
pubmed: 15846786
Psychoneuroendocrinology. 1995;20(7):735-42
pubmed: 8848519
Neuron. 2018 Sep 19;99(6):1315-1328.e5
pubmed: 30146300
Paediatr Child Health. 2010 Mar;15(3):153-6
pubmed: 21358895
Physiol Behav. 1996 Jun;59(6):1189-92
pubmed: 8737912
J Neurosci Methods. 2017 Mar 1;279:1-12
pubmed: 28089759
Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13811-6
pubmed: 26504228
Nat Neurosci. 2018 Mar;21(3):415-423
pubmed: 29459764
Neuron. 2018 Feb 7;97(3):656-669.e7
pubmed: 29420934
Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):E3640-8
pubmed: 23184972
Exp Brain Res. 2010 Dec;207(3-4):149-55
pubmed: 20963582
Mol Psychiatry. 2001 Jan;6(1):13-34
pubmed: 11244481
Genet Soc Gen Psychol Monogr. 2006 Feb;132(1):5-94
pubmed: 17345871
Dev Cogn Neurosci. 2020 Apr;42:100776
pubmed: 32452462
Front Vet Sci. 2015 Oct 28;2:50
pubmed: 26664977
J Neurosci. 2016 Jun 15;36(24):6420-30
pubmed: 27307231
J Am Acad Child Adolesc Psychiatry. 2000 Jun;39(6):703-12
pubmed: 10846304
J Neurosci. 1988 Jul;8(7):2517-29
pubmed: 2854842
Psychoneuroendocrinology. 2013 Sep;38(9):1748-56
pubmed: 23490074
Front Neuroanat. 2019 May 08;13:43
pubmed: 31133822
Behav Neurosci. 2002 Jun;116(3):489-93
pubmed: 12049330
Neuroscience. 2016 Aug 25;330:267-90
pubmed: 27256508
Neurosci Biobehav Rev. 2010 Feb;34(2):185-91
pubmed: 18952123
Hum Brain Mapp. 2013 Apr;34(4):914-22
pubmed: 22125232
J Neurophysiol. 2007 Feb;97(2):1671-83
pubmed: 17093126
Arch Neurol. 2009 May;66(5):557-60
pubmed: 19433654
J Pediatr. 1949 Oct;35(4):512-21
pubmed: 18143946
Neuroscience. 2002;115(4):1261-79
pubmed: 12453496
Dev Cogn Neurosci. 2019 Feb;35:5-11
pubmed: 29731417
Proc Natl Acad Sci U S A. 2020 Jan 7;117(1):641-649
pubmed: 31907309
eNeuro. 2016 Oct 7;3(5):
pubmed: 27752543
Neuroimage. 2021 May 1;231:117818
pubmed: 33548458
Biol Psychiatry. 2003 Dec 15;54(12):1389-98
pubmed: 14675803
Trends Cogn Sci. 2005 Dec;9(12):585-94
pubmed: 16289871
Nature. 2001 Jun 21;411(6840):953-6
pubmed: 11418860
Neurosci Biobehav Rev. 2010 Feb;34(2):260-8
pubmed: 18662717
Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):E1657-66
pubmed: 22665808
Science. 2017 May 19;356(6339):745-749
pubmed: 28522533
Monogr Soc Res Child Dev. 2011 Dec;76(4):92-126
pubmed: 25364058
Curr Opin Behav Sci. 2019 Apr;26:97-106
pubmed: 32832584
Biol Psychol. 2018 Sep;137:83-90
pubmed: 30003943
Nat Neurosci. 2015 Jul;18(7):1041-50
pubmed: 26053402
Curr Biol. 2007 Oct 23;17(20):R868-74
pubmed: 17956742
Front Psychol. 2016 Jan 06;6:1986
pubmed: 26779092
J Neuropsychol. 2020 Mar;14(1):165-182
pubmed: 30714317
J Child Psychol Psychiatry. 1998 May;39(4):465-76
pubmed: 9599775
Front Neurosci. 2020 Dec 04;14:589878
pubmed: 33343285
Trends Neurosci. 2021 Jan;44(1):17-28
pubmed: 33378653
Neuropsychologia. 2014 Oct;63:235-48
pubmed: 25152530
Nat Neurosci. 2002 Sep;5(9):900-4
pubmed: 12145636
Nat Neurosci. 2021 Jan;24(1):5-18
pubmed: 33169032
Neuroscience. 2021 Jun 1;464:105-116
pubmed: 32931848
Front Hum Neurosci. 2016 May 10;10:209
pubmed: 27242474
Biol Psychol. 2017 Sep;128:71-81
pubmed: 28723347
J Neurosci. 2019 May 8;39(19):3663-3675
pubmed: 30858163
Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18956-61
pubmed: 23112157
Psychoneuroendocrinology. 2014 Jan;39:11-20
pubmed: 24275000
Dev Sci. 2011 Mar;14(2):190-204
pubmed: 21399712
Psychoneuroendocrinology. 1989;14(1-2):155-61
pubmed: 2525263
Nat Rev Neurosci. 2020 Oct;21(10):565-575
pubmed: 32839565
Handb Exp Pharmacol. 2015;227:261-84
pubmed: 25846623
Nat Rev Neurosci. 2002 Aug;3(8):655-66
pubmed: 12154366
Cereb Cortex. 2003 Mar;13(3):308-17
pubmed: 12571120
Prog Brain Res. 1996;107:447-60
pubmed: 8782536
Dev Psychobiol. 1995 Mar;28(2):71-84
pubmed: 8529786