Biliary Anastomosis Using T-tube Versus No T-tube for Liver Transplantation in Adults: A Review of Literature.

biliary anastomosis biliary complications biliary strictures biliary tract reconstruction orthotopic liver transplantation

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
Apr 2022
Historique:
accepted: 18 04 2022
entrez: 23 5 2022
pubmed: 24 5 2022
medline: 24 5 2022
Statut: epublish

Résumé

The T-tube-directed biliary anastomosis in orthotopic liver transplantation (OLT) aims to minimize preventable biliary complications, including bile leaks and strictures. Biliary complications in patients with OLT increase the risk of morbidity and mortality. This review paper evaluated the current evidence on the routine use of T-tube reconstruction in OLT cases. A review of prospective, retrospective, observational, cohort studies as well as systematic reviews, meta-analyses, review papers, and opinion papers has been conducted to evaluate the therapeutic potential of T tube-based biliary anastomosis in cases of OLT. Our finding showed a bile leak incidence of 16.6% and 6.6% in T-tube and non-T-tube groups, respectively. The results indicated a lower incidence of anastomotic fistulae in the non-T-tube group (0.6%) compared to the T-tube group (4%). The findings negated statistically significant differences in the three-year actuarial survival rates based on biliary anastomosis with and without T-tube intervention (62.5% vs. 69.8%). The studies revealed a 6-11% and 2-11% incidence of cholangitis in OLT patients with T-tube-based reconstruction and those without a T-tube, respectively, and 26% and 20% incidence of total biliary complications in OLT patients with and without T-tube, respectively. In addition, the findings ruled out the influence of a T-tube on the incidence of perioperative complications, endoscopies, and reoperations in OLT cases. The current evidence correlates the increased incidence of bile leaks, cholangitis, and overall biliary complications with the use of a T-tube during OLT. In addition, T-tube-guided reconstruction has no impact on perioperative complications, overall survival, endoscopies, and reoperations in OLT cases.

Identifiants

pubmed: 35602800
doi: 10.7759/cureus.24253
pmc: PMC9117859
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

e24253

Informations de copyright

Copyright © 2022, Vest et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Références

ANZ J Surg. 2018 Jun;88(6):603-606
pubmed: 29667284
Postgrad Med J. 2007 Feb;83(976):120-3
pubmed: 17308216
Ann Surg. 2013 Jul;258(1):21-9
pubmed: 23426348
Expert Rev Gastroenterol Hepatol. 2015 Apr;9(4):529-38
pubmed: 25583036
Transpl Int. 2005 Jun;18(6):627-42
pubmed: 15910286
Transplant Proc. 2016 Nov;48(9):3003-3005
pubmed: 27932131
JAMA Surg. 2019 May 1;154(5):431-439
pubmed: 30758485
Am Surg. 2010 Sep;76(9):969-73
pubmed: 20836345
Transpl Int. 1996;9(4):392-5
pubmed: 8819276
J Clin Transl Hepatol. 2019 Mar 28;7(1):61-71
pubmed: 30944822
World J Gastroenterol. 2013 May 21;19(19):2841-6
pubmed: 23704818
Hepatobiliary Surg Nutr. 2013 Jun;2(3):171-3
pubmed: 24570938
Radiographics. 2012 Jan-Feb;32(1):199-211
pubmed: 22236901
Liver Transpl. 2010 Jun;16(6):705-17
pubmed: 20517904
J Zhejiang Univ Sci B. 2011 May;12(5):357-64
pubmed: 21528489
World J Gastroenterol. 2021 Apr 14;27(14):1507-1523
pubmed: 33911471
Transplant Proc. 2007 Dec;39(10):3251-6
pubmed: 18089365
Transpl Int. 1998;11(2):123-6
pubmed: 9561678
Expert Rev Gastroenterol Hepatol. 2021 Oct;15(10):1201-1213
pubmed: 33720798
Transplant Proc. 2010 Jul-Aug;42(6):2381-2
pubmed: 20692485
Clin Transplant. 2007 Jul-Aug;21(4):548-53
pubmed: 17645718
Transplant Proc. 2019 Jan - Feb;51(1):44-49
pubmed: 30736977
Ann Surg. 2001 Mar;233(3):432-7
pubmed: 11224633
Transplant Proc. 2012 Sep;44(7):2098-9
pubmed: 22974922
Ann Surg. 2009 Nov;250(5):766-71
pubmed: 19809299
Transplant Proc. 2005 Nov;37(9):3922-3
pubmed: 16386585
Transplant Proc. 1997 Feb-Mar;29(1-2):564-5
pubmed: 9123131
Transplantation. 1998 Jan 27;65(2):193-9
pubmed: 9458013
J Gastrointest Surg. 2017 Apr;21(4):723-730
pubmed: 27815760
Transplantation. 1996 Jan 27;61(2):258-61
pubmed: 8600634
Am J Transplant. 2001 Jul;1(2):157-61
pubmed: 12099364
Dig Surg. 2008;25(4):245-57
pubmed: 18628624
World J Gastroenterol. 2009 Aug 14;15(30):3725-33
pubmed: 19673012

Auteurs

Mallorie Vest (M)

Internal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, USA.

Camelia Ciobanu (C)

Medicine, St. Barnabas Hospital, New York City, USA.

Akwe Nyabera (A)

Internal Medicine, New York City Health and Hospitals/Queens, New York City, USA.

John Williams (J)

Internal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, USA.

Matthew Marck (M)

Internal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, USA.

Ian Landry (I)

Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, USA.

Vikram Sumbly (V)

Internal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, USA.

Saba Iqbal (S)

Internal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, USA.

Deesha Shah (D)

Internal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, USA.

Mahmoud Nassar (M)

Internal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, USA.

Nso Nso (N)

Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, USA.

Vincent Rizzo (V)

Internal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, USA.

Classifications MeSH