Brain MRI in Monogenic Cerebral Small Vessel Diseases: A Practical Handbook.
CADASIL
CARASAL
CARASIL
COL4
Fabry Disease
MRI
RCVL-S
Small vessels disease
monogenic
Journal
Current molecular medicine
ISSN: 1875-5666
Titre abrégé: Curr Mol Med
Pays: Netherlands
ID NLM: 101093076
Informations de publication
Date de publication:
2022
2022
Historique:
received:
02
09
2020
revised:
28
01
2021
accepted:
09
02
2021
entrez:
23
5
2022
pubmed:
24
5
2022
medline:
25
5
2022
Statut:
ppublish
Résumé
Monogenic cerebral small vessel diseases are a topic of growing interest, as several genes responsible have been recently described, and new sequencing techniques such as Next-generation sequencing are available. Brain imaging is significant for the detection of these diseases. Since it is often performed at an initial stage, an MRI is a key to selecting patients for genetic testing and for interpreting nextgeneration sequencing reports. In addition, neuroimaging can be helpful in describing the underlying pathological mechanisms involved in cerebral small vessel disease. In this review, we aim to provide neurologists and stroke physicians with an up-to-date overview of the current neuroimaging knowledge on monogenic small vessel diseases.
Identifiants
pubmed: 35603886
pii: CMM-EPUB-115602
doi: 10.2174/1566524021666210510164003
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
300-311Informations de copyright
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