Selective endocytosis of Ca


Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
27 05 2022
Historique:
entrez: 25 5 2022
pubmed: 26 5 2022
medline: 28 5 2022
Statut: ppublish

Résumé

AMPA-type glutamate receptors (AMPARs) mediate fast excitatory neurotransmission, and the plastic modulation of their surface levels determines synaptic strength. AMPARs of different subunit compositions fulfill distinct roles in synaptic long-term potentiation (LTP) and depression (LTD) to enable learning. Largely unknown endocytic mechanisms mediate the subunit-selective regulation of the surface levels of GluA1-homomeric Ca

Identifiants

pubmed: 35613266
doi: 10.1126/sciadv.abl5032
pmc: PMC9132451
doi:

Substances chimiques

Receptors, AMPA 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eabl5032

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM058202
Pays : United States

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Auteurs

Domenico Azarnia Tehran (D)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.

Gaga Kochlamazashvili (G)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.

Niccolò P Pampaloni (NP)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.
Institute of Biology, Cellular Biophysics, Humboldt Universität zu Berlin, 10115 Berlin, Germany.

Silvia Sposini (S)

University of Bordeaux, Interdisciplinary Institute for Neuroscience, UMR 5297, Bordeaux, France.
CNRS, Interdisciplinary Institute for Neuroscience, UMR 5297, Bordeaux, France.

Jasmeet Kaur Shergill (JK)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.
Department of Nanophysiology, Technische Universität Kaiserslautern, Paul-Ehrlich-Strasse 23, 67663 Kaiserslautern, Germany.

Martin Lehmann (M)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.

Natalya Pashkova (N)

Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.

Claudia Schmidt (C)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.

Delia Löwe (D)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.

Hanna Napieczynska (H)

Animal Phenotyping, Max Delbrück Center for Molecular Medicine, Robert-Roessle-Straße 10, 13125 Berlin, Germany.

Arnd Heuser (A)

Animal Phenotyping, Max Delbrück Center for Molecular Medicine, Robert-Roessle-Straße 10, 13125 Berlin, Germany.

Andrew J R Plested (AJR)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.
Institute of Biology, Cellular Biophysics, Humboldt Universität zu Berlin, 10115 Berlin, Germany.
NeuroCure Cluster of Excellence, Charité Universitätsmedizin Berlin, Virchowweg 6, 10117 Berlin, Germany.

David Perrais (D)

University of Bordeaux, Interdisciplinary Institute for Neuroscience, UMR 5297, Bordeaux, France.
CNRS, Interdisciplinary Institute for Neuroscience, UMR 5297, Bordeaux, France.

Robert C Piper (RC)

Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.

Volker Haucke (V)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.
NeuroCure Cluster of Excellence, Charité Universitätsmedizin Berlin, Virchowweg 6, 10117 Berlin, Germany.
Freie Universität Berlin, Faculty of Biology, Chemistry and Pharmacy, 14195 Berlin, Germany.

Tanja Maritzen (T)

Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.
Department of Nanophysiology, Technische Universität Kaiserslautern, Paul-Ehrlich-Strasse 23, 67663 Kaiserslautern, Germany.

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