Variability in Test Interval Is Linked to Glycated Haemoglobin (HbA1c) Trajectory over Time.


Journal

Journal of diabetes research
ISSN: 2314-6753
Titre abrégé: J Diabetes Res
Pays: England
ID NLM: 101605237

Informations de publication

Date de publication:
2022
Historique:
received: 03 02 2022
accepted: 20 04 2022
entrez: 26 5 2022
pubmed: 27 5 2022
medline: 28 5 2022
Statut: epublish

Résumé

We previously showed that the glycated haemoglobin (HbA1c) testing frequency links to diabetes control. Here, we examine the effect of variability in test interval, adjusted for the frequency, on change in HbA1c ( In general, less variability in testing frequency (more consistent monitoring) was associated with better diabetes control. This was most evident with moderately raised baseline HbA1c levels (7.0-9.0% (54-75 mmol/mol)). For example, in those with a starting HbA1c of 7.0-7.5% (54-58 mmol/mol), the lowest SD decile was associated with little change in HbA1c over 5 years, while for those with the highest decile, HbA1c rose by 0.4-0.6% (4-6 mmol/mol; These findings indicate that the consistency of testing interval, not the just number of tests/year, is important in maintaining diabetes control, especially in those with moderately raised HbA1c levels. Systems to improve regularity of HbA1c testing are therefore needed, especially given the impact of COVID-19 on diabetes monitoring.

Identifiants

pubmed: 35615258
doi: 10.1155/2022/7093707
pmc: PMC9126657
doi:

Substances chimiques

Glycated Hemoglobin A 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

7093707

Informations de copyright

Copyright © 2022 Anthony A. Fryer et al.

Déclaration de conflit d'intérêts

The authors have no conflicts of interest to declare.

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Auteurs

Anthony A Fryer (AA)

School of Medicine, Keele University, Keele, Staffordshire, UK.
Department of Clinical Biochemistry, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, Staffordshire, UK.

David Holland (D)

The Benchmarking Partnership, Alsager, Cheshire, UK.

Christopher J Duff (CJ)

School of Medicine, Keele University, Keele, Staffordshire, UK.
Department of Clinical Biochemistry, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, Staffordshire, UK.

Lewis Green (L)

Department of Clinical Biochemistry, St. Helens & Knowsley Teaching Hospitals NHS Trust, Whiston Hospital, Prescot, UK.

Jonathan Scargill (J)

Department of Clinical Biochemistry, The Royal Oldham Hospital, The Northern Care Alliance NHS Group, Oldham, UK.

Fahmy W F Hanna (FWF)

Department of Diabetes and Endocrinology, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, Staffordshire, UK.
Centre for Health & Development, Staffordshire University, Staffordshire, UK.

Pensée Wu (P)

School of Medicine, Keele University, Keele, Staffordshire, UK.
Department of Obstetrics & Gynaecology, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, Staffordshire, UK.

R John Pemberton (RJ)

Diabetes UK (North Staffordshire Branch), Porthill, Stoke-on-Trent, Staffordshire, UK.

Christine Bloor (C)

Diabetes UK (North Staffordshire Branch), Porthill, Stoke-on-Trent, Staffordshire, UK.

Adrian H Heald (AH)

Department of Diabetes and Endocrinology, Salford Royal NHS Foundation Trust, Salford, UK.
The School of Medicine and Manchester Academic Health Sciences Centre, The University of Manchester, Manchester, UK.

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