Characteristics of Patients with Meningeal Carcinomatosis Combined with Myelopathy.
CSF cytology
histopathological investigation
meningeal carcinomatosis
myelopathy
Journal
Neuropsychiatric disease and treatment
ISSN: 1176-6328
Titre abrégé: Neuropsychiatr Dis Treat
Pays: New Zealand
ID NLM: 101240304
Informations de publication
Date de publication:
2022
2022
Historique:
received:
13
07
2021
accepted:
22
10
2021
entrez:
26
5
2022
pubmed:
27
5
2022
medline:
27
5
2022
Statut:
epublish
Résumé
To explore the disease manifestations and radiological characteristics of patients with meningeal carcinomatosis (MC) combined with myelopathy. The detailed medical information of patients who suffered from MC with myelopathy in record system were collected and reviewed. In these patients, five cases were male and two cases were female. The age was from fifteen to fifty-seven years. In the course of disease, tumor cells were discovered in cerebrospinal fluid of three patients and in biopsy samples of four patients. Cerebrospinal fluid (CSF) test results showed white blood cell counts increased in seven patients, protein increased in six patients and glucose reduced in five patients. In addition, MRI revealed that the white matter abnormalities showed in all cases and pia mater was enhanced in four patients, meningeal enhanced was observed in three patients. All patients were given appropriate therapy during hospitalization. Follow-up result showed that all patients passed away two to five months after diagnosis. MC causes spinal membrane, spinal nerve root to be involved besides, also can produce the matter of myelopathy. Early detection of intramedullary lesion is conducive to strengthening the awareness of the diagnosis of MC.
Identifiants
pubmed: 35615422
doi: 10.2147/NDT.S329180
pii: 329180
pmc: PMC9126291
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1069-1075Informations de copyright
© 2022 Jiao et al.
Déclaration de conflit d'intérêts
All authors state that there is no conflict of interest.
Références
Neurol Sci. 2015 Jan;36(1):117-23
pubmed: 25022241
Neuropathology. 2014 Oct;34(5):499-503
pubmed: 24779918
Radiology. 2003 Jan;226(1):181-7
pubmed: 12511688
Arq Neuropsiquiatr. 2011 Dec;69(6):973-80
pubmed: 22297890
Semin Oncol. 2009 Aug;36(4 Suppl 2):S35-45
pubmed: 19660682
Spine J. 2014 Aug 1;14(8):1808-9
pubmed: 24747265
Curr Oncol Rep. 2010 Jan;12(1):41-9
pubmed: 20425607
Neuropathology. 2008 Jun;28(3):295-302
pubmed: 18179410
J Neurooncol. 2004 Oct;70(1):67-71
pubmed: 15527109
Ann Oncol. 2017 Jul 1;28(suppl_4):iv84-iv99
pubmed: 28881917
Curr Opin Oncol. 2010 Nov;22(6):627-35
pubmed: 20689429
Ann Oncol. 2004;15 Suppl 4:iv285-91
pubmed: 15477323
Acta Neurol Belg. 2015 Sep;115(3):415-9
pubmed: 25344827
Neurosurg Focus. 1998 Jun 15;4(6):e4
pubmed: 17154444
J Neurooncol. 2011 Sep;104(2):565-72
pubmed: 21234642
Neuroradiology. 1997 Jun;39(6):437-40
pubmed: 9225326
World J Surg Oncol. 2018 Apr 13;16(1):78
pubmed: 29653576
Neuroradiology. 1990;32(1):26-32
pubmed: 2333130
Clin Neuroradiol. 2014 Sep;24(3):281-4
pubmed: 23913019
BMC Neurol. 2019 Dec 19;19(1):331
pubmed: 31856745
J Nucl Med Technol. 2015 Sep;43(3):227-8
pubmed: 25655343
J Clin Neurosci. 2015 Apr;22(4):632-7
pubmed: 25677875