Phase transition modulation and biophysical characterization of biomolecular condensates using microfluidics.

Biomolecular Condensates Biophysics Humans Microfluidics Neurodegenerative Diseases Organelles Phase Transition

Journal

Lab on a chip
ISSN: 1473-0189
Titre abrégé: Lab Chip
Pays: England
ID NLM: 101128948

Informations de publication

Date de publication:
12 07 2022
Historique:
pubmed: 27 5 2022
medline: 14 7 2022
entrez: 26 5 2022
Statut: epublish

Résumé

Membraneless organelles (MLOs) formed through liquid-liquid phase separation (LLPS) are becoming increasingly relevant to understanding viral-host interactions, neurodegenerative disease, and cancer. The modulation of LLPS involves many parameters and components. To describe these modulators, typical

Identifiants

DOI: 10.1039/d2lc00037g PMID: 35616128
pubmed: 35616128
doi: 10.1039/d2lc00037g
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2647-2656

Auteurs

Katherine W Y Chan (KWY)

Graduate Program in Biomedical Engineering, Ryerson University, Toronto M5B 2K3, Canada. scott.tsai@ryerson.ca.
Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto M5B 2K3, Canada.
Institute for Biomedical Engineering, Science, and Technology (iBEST) - A partnership between Ryerson University and St. Michael's Hospital, Toronto M5B 1W8, Canada.
ORCID: 0000-0003-2498-4748

Maryam Navi (M)

Graduate Program in Biomedical Engineering, Ryerson University, Toronto M5B 2K3, Canada. scott.tsai@ryerson.ca.
Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto M5B 2K3, Canada.
Institute for Biomedical Engineering, Science, and Technology (iBEST) - A partnership between Ryerson University and St. Michael's Hospital, Toronto M5B 1W8, Canada.
ORCID: 0000-0003-2418-3916

Jennifer Kieda (J)

Graduate Program in Biomedical Engineering, Ryerson University, Toronto M5B 2K3, Canada. scott.tsai@ryerson.ca.
Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto M5B 2K3, Canada.
Institute for Biomedical Engineering, Science, and Technology (iBEST) - A partnership between Ryerson University and St. Michael's Hospital, Toronto M5B 1W8, Canada.
ORCID: 0000-0003-4748-3460

Thomas Moran (T)

Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana 46556, USA.

Daniel Hammers (D)

Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana 46556, USA.
Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana 46556, USA.

Shaun Lee (S)

Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana 46556, USA.
Eck Institute for Global Health, University of Notre Dame, Notre Dame, Indiana 46556, USA.
Institution for Precision Health, University of Notre Dame, Notre Dame, Indiana 46556, USA.

Scott S H Tsai (SSH)

Graduate Program in Biomedical Engineering, Ryerson University, Toronto M5B 2K3, Canada. scott.tsai@ryerson.ca.
Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto M5B 2K3, Canada.
Institute for Biomedical Engineering, Science, and Technology (iBEST) - A partnership between Ryerson University and St. Michael's Hospital, Toronto M5B 1W8, Canada.
Department of Mechanical and Industrial Engineering, Ryerson University, Toronto M5B 2K3, Canada.
ORCID: 0000-0001-6607-8191

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Classifications MeSH

questionsmedicales.fr › Cellules › Structures cellulaires › Condensats biomoléculaires › Phase transition modulation and biophysical...
questionsmedicales.fr › Disciplines des sciences naturelles › Physique › Biophysique › Phase transition modulation and biophysical...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Phase transition modulation and biophysical...
questionsmedicales.fr › Technologie, industrie et agriculture › Technologie › Miniaturisation › Microtechnologie › Microfluidique › Phase transition modulation and biophysical...
questionsmedicales.fr › Maladies du système nerveux › Maladies neurodégénératives › Phase transition modulation and biophysical...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Phase transition modulation and biophysical...
questionsmedicales.fr › Phénomènes chimiques › Transition de phase › Phase transition modulation and biophysical...