Age related changes in gait variability, asymmetry, and bilateral coordination - When does deterioration starts?

Aging Bilateral coordination of gait Gait Gait asymmetry Phase coordination index

Journal

Gait & posture
ISSN: 1879-2219
Titre abrégé: Gait Posture
Pays: England
ID NLM: 9416830

Informations de publication

Date de publication:
07 2022
Historique:
received: 13 01 2022
revised: 14 04 2022
accepted: 05 05 2022
pubmed: 27 5 2022
medline: 3 8 2022
entrez: 26 5 2022
Statut: ppublish

Résumé

Gait pattern coordination is affected by several factors (e.g., neurodegeneration), while aging is known to have a significant negative impact. Various gait parameters, such as gait asymmetry (GA) and stride time coefficient of variation (CV), are widely used in both research and clinical settings in order to evaluate human locomotion. Another parameter is the phase coordination index (PCI), which specifically assesses bilateral coordination of gait (BCG), by quantifying the consistency and accuracy of the anti-phased stepping pattern. In this study we hypothesized that there is a steady deterioration in the bilateral coordination of walking through ageing, and in gait rhythmicity, which would be evident by an increase in the values of the coordination parameters which are examined. We analyzed gait cycles of 66 healthy participants in ages between 40 and 85 years which were divided into five age groups (40-44; 45-54; 55-64; 75 +). The participants performed corridor walking (i.e., back and forth) wearing a computerized motion sensor-based gait analysis system. PCI, CV and GA parameters were calculated for the straight-line walking segments. PCI values remained relatively stable between the ages of 40-75 (3.16 ± 1.11%), while in the age group of 75 + years old we observed a significant increase (i.e., deterioration in BCG) in PCI values (5.68 ± 2.01%, p < 0.047). Same pattern was seen for the CV parameter. However, GA was not statistically significantly different between all age groups. It appears that PCI and CV are more sensitive measures to detect changes in gait through the aging process. The results suggest that potential screening to detect salient gait deterioration should start from the age of 70. On the other hand, GA may be used to identify neurological impairments if found increased at any age.

Sections du résumé

BACKGROUND
Gait pattern coordination is affected by several factors (e.g., neurodegeneration), while aging is known to have a significant negative impact. Various gait parameters, such as gait asymmetry (GA) and stride time coefficient of variation (CV), are widely used in both research and clinical settings in order to evaluate human locomotion. Another parameter is the phase coordination index (PCI), which specifically assesses bilateral coordination of gait (BCG), by quantifying the consistency and accuracy of the anti-phased stepping pattern.
OBJECTIVE
In this study we hypothesized that there is a steady deterioration in the bilateral coordination of walking through ageing, and in gait rhythmicity, which would be evident by an increase in the values of the coordination parameters which are examined.
METHODS
We analyzed gait cycles of 66 healthy participants in ages between 40 and 85 years which were divided into five age groups (40-44; 45-54; 55-64; 75 +). The participants performed corridor walking (i.e., back and forth) wearing a computerized motion sensor-based gait analysis system. PCI, CV and GA parameters were calculated for the straight-line walking segments.
RESULTS
PCI values remained relatively stable between the ages of 40-75 (3.16 ± 1.11%), while in the age group of 75 + years old we observed a significant increase (i.e., deterioration in BCG) in PCI values (5.68 ± 2.01%, p < 0.047). Same pattern was seen for the CV parameter. However, GA was not statistically significantly different between all age groups.
CONCLUSION
It appears that PCI and CV are more sensitive measures to detect changes in gait through the aging process. The results suggest that potential screening to detect salient gait deterioration should start from the age of 70. On the other hand, GA may be used to identify neurological impairments if found increased at any age.

Identifiants

pubmed: 35617787
pii: S0966-6362(22)00132-1
doi: 10.1016/j.gaitpost.2022.05.009
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

87-92

Informations de copyright

Copyright © 2022 Elsevier B.V. All rights reserved.

Auteurs

Sean Zadik (S)

Center of Advanced Technologies in Rehabilitation Sheba Medical Center, Ramat Gan, Israel.

Amit Benady (A)

Center of Advanced Technologies in Rehabilitation Sheba Medical Center, Ramat Gan, Israel; School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Shmuel Gutwillig (S)

School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Michelle M Florentine (MM)

Center of Advanced Technologies in Rehabilitation Sheba Medical Center, Ramat Gan, Israel; School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Ryan Eli Solymani (RE)

Center of Advanced Technologies in Rehabilitation Sheba Medical Center, Ramat Gan, Israel; School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Meir Plotnik (M)

Center of Advanced Technologies in Rehabilitation Sheba Medical Center, Ramat Gan, Israel; Dept. of Physiology and Pharmacology, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; The Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel. Electronic address: meir.plotnikpeleg@sheba.health.gov.il.

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Classifications MeSH