Risk scores for predicting small for gestational age infants in Japan: The TMM birthree cohort study.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
26 05 2022
Historique:
received: 27 06 2021
accepted: 16 05 2022
entrez: 26 5 2022
pubmed: 27 5 2022
medline: 31 5 2022
Statut: epublish

Résumé

This study aimed to construct a prediction model for small-for-gestational-age (SGA) infants in Japan by creating a risk score during pregnancy. A total of 17,073 subjects were included in the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study, a prospective cohort study. A multiple logistic regression model was used to construct risk scores during early and mid-gestational periods (11-17 and 18-21 weeks of gestation, respectively). The risk score during early gestation comprised the maternal age, height, body mass index (BMI) during early gestation, parity, assisted reproductive technology (ART) with frozen-thawed embryo transfer (FET), smoking status, blood pressure (BP) during early gestation, and maternal birth weight. The risk score during mid-gestation also consisted of the maternal age, height, BMI during mid-gestation, weight gain, parity, ART with FET, smoking status, BP level during mid-gestation, maternal birth weight, and estimated fetal weight during mid-gestation. The C-statistics of the risk scores during early- and mid-gestation were 0.658 (95% confidence interval [CI]: 0.642-0.675) and 0.725 (95% CI: 0.710-0.740), respectively. In conclusion, the predictive ability of the risk scores during mid-gestation for SGA infants was acceptable and better than that of the risk score during early gestation.

Identifiants

pubmed: 35618764
doi: 10.1038/s41598-022-12892-0
pii: 10.1038/s41598-022-12892-0
pmc: PMC9135745
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

8921

Informations de copyright

© 2022. The Author(s).

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Auteurs

Noriyuki Iwama (N)

Department of Obstetrics and Gynecology, Tohoku University Hospital, 1-1, Seiryomachi, Sendai, Miyagi, 980-8574, Japan. noriyuki.iwama@med.tohoku.ac.jp.
Division of Molecular Epidemiology, Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan. noriyuki.iwama@med.tohoku.ac.jp.

Taku Obara (T)

Division of Molecular Epidemiology, Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Division of Molecular Epidemiology, Graduate School of Medicine, Tohoku University, Sendai, Japan.
Department of Pharmaceutical Sciences, Tohoku University Hospital, Sendai, Miyagi, Japan.

Mami Ishikuro (M)

Division of Molecular Epidemiology, Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Division of Molecular Epidemiology, Graduate School of Medicine, Tohoku University, Sendai, Japan.

Keiko Murakami (K)

Division of Molecular Epidemiology, Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Division of Molecular Epidemiology, Graduate School of Medicine, Tohoku University, Sendai, Japan.

Fumihiko Ueno (F)

Division of Molecular Epidemiology, Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Division of Molecular Epidemiology, Graduate School of Medicine, Tohoku University, Sendai, Japan.

Aoi Noda (A)

Division of Molecular Epidemiology, Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Division of Molecular Epidemiology, Graduate School of Medicine, Tohoku University, Sendai, Japan.
Department of Pharmaceutical Sciences, Tohoku University Hospital, Sendai, Miyagi, Japan.

Tomomi Onuma (T)

Division of Molecular Epidemiology, Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Division of Molecular Epidemiology, Graduate School of Medicine, Tohoku University, Sendai, Japan.

Fumiko Matsuzaki (F)

Division of Molecular Epidemiology, Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.

Tetsuro Hoshiai (T)

Department of Obstetrics and Gynecology, Tohoku University Hospital, 1-1, Seiryomachi, Sendai, Miyagi, 980-8574, Japan.

Masatoshi Saito (M)

Department of Obstetrics and Gynecology, Tohoku University Hospital, 1-1, Seiryomachi, Sendai, Miyagi, 980-8574, Japan.
Department of Maternal and Fetal Therapeutics, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.

Hirohito Metoki (H)

Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan.
Division of Public Health, Hygiene and Epidemiology, Tohoku Medical Pharmaceutical University, Sendai, Miyagi, Japan.

Junichi Sugawara (J)

Department of Obstetrics and Gynecology, Tohoku University Hospital, 1-1, Seiryomachi, Sendai, Miyagi, 980-8574, Japan.
Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan.
Environment and Genome Research Center, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.

Nobuo Yaegashi (N)

Department of Obstetrics and Gynecology, Tohoku University Hospital, 1-1, Seiryomachi, Sendai, Miyagi, 980-8574, Japan.
Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan.
Environment and Genome Research Center, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.
Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan.

Shinichi Kuriyama (S)

Division of Molecular Epidemiology, Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Division of Molecular Epidemiology, Graduate School of Medicine, Tohoku University, Sendai, Japan.
International Research Institute of Disaster Science, Tohoku University, Sendai, Miyagi, Japan.

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