Suicide by Pesticide (Phorate) Ingestion: Case Report and Review of Literature.

pesticides phorate suicidal ingestion

Journal

Toxics
ISSN: 2305-6304
Titre abrégé: Toxics
Pays: Switzerland
ID NLM: 101639637

Informations de publication

Date de publication:
21 Apr 2022
Historique:
received: 04 03 2022
revised: 08 04 2022
accepted: 11 04 2022
entrez: 27 5 2022
pubmed: 28 5 2022
medline: 28 5 2022
Statut: epublish

Résumé

It has been estimated that approximately one in seven of all global suicides is due to pesticide self-poisoning, mostly in rural areas of developing countries. Organophosphorus (OP) compounds are a group of pesticides exerting their toxicological effects through non-reversible inhibition of the enzyme acetylcholinesterase (AChE). Among these compounds, phorate (thimet) is one of the most dangerous compounds, the use of which is restricted in many countries. A case of intentional suicide after phorate ingestion in a 24-year-old Bengali male is described. This is the second case of suicidal ingestion of phorate reported in the forensic literature, and the first presenting complete toxicological findings.

Identifiants

pubmed: 35622619
pii: toxics10050205
doi: 10.3390/toxics10050205
pmc: PMC9146379
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

Healthcare (Basel). 2021 Jan 29;9(2):
pubmed: 33572719
Trop Med Int Health. 2005 Jun;10(6):581-8
pubmed: 15941422
Intensive Care Med. 2001 Apr;27(4):694-9
pubmed: 11398695
Toxicol Lett. 1995 Dec;82-83:73-81
pubmed: 8597134
J Toxicol Clin Toxicol. 2004;42(6):865-75
pubmed: 15533026
BMJ. 2004 Jan 3;328(7430):42-4
pubmed: 14703547
Anal Chem. 2011 Nov 15;83(22):8566-74
pubmed: 21992470
Lancet Glob Health. 2017 Oct;5(10):e1026-e1037
pubmed: 28807587
Forensic Sci Int. 2019 Jul;300:120-124
pubmed: 31102900
Am Ind Hyg Assoc J. 1979 Nov;40(11):1013-6
pubmed: 532778
Sci Total Environ. 2017 Jan 1;575:525-535
pubmed: 27614863
Biochem Pharmacol. 2004 Sep 1;68(5):959-67
pubmed: 15294458
Fundam Appl Toxicol. 1984 Apr;4(2 Pt 2):S209-14
pubmed: 6724213
Lancet. 2008 Feb 16;371(9612):622
pubmed: 18280331
Crit Care. 2020 May 6;24(1):195
pubmed: 32375836
Sci Total Environ. 1994 Jun 20;149(3):183-91
pubmed: 8052834
Am J Ind Med. 2005 Apr;47(4):308-21
pubmed: 15776467
JNMA J Nepal Med Assoc. 2012 Jan-Mar;52(185):49-51
pubmed: 23279775
J Toxicol Clin Toxicol. 1997;35(7):711-9
pubmed: 9482426
Curr Neuropharmacol. 2013 May;11(3):315-35
pubmed: 24179466
Forensic Sci Int. 2019 Apr;297:e1-e7
pubmed: 30777401
J Affect Disord. 2017 Sep;219:93-104
pubmed: 28535450
Clin Toxicol (Phila). 2009 Mar;47(3):179-92
pubmed: 18988062
Forensic Sci Int. 1996 May 17;79(1):53-63
pubmed: 8635774
J Agromedicine. 2006;11(3-4):107-12
pubmed: 19274902
Hum Exp Toxicol. 1995 May;14(5):437-45
pubmed: 7612307

Auteurs

Angela Simonelli (A)

Department of Advanced Biomedical Science, Legal Medicine Section, University of Naples "Federico II", Via S. Pansini, 5, 80138 Napoli, Italy.

Anna Carfora (A)

Forensic Toxicology Unit, Department of Experimental Medicine, University of Campania "L. Vanvitelli", Via L. Armanni, 5, 80138 Napoli, Italy.

Pascale Basilicata (P)

Department of Advanced Biomedical Science, Legal Medicine Section, University of Naples "Federico II", Via S. Pansini, 5, 80138 Napoli, Italy.

Bruno Liguori (B)

Department of Experimental Medicine, Institute of Legal Medicine, University of Campania "L. Vanvitelli", Via L. Armanni, 5, 80138 Napoli, Italy.

Pasquale Mascolo (P)

Department of Experimental Medicine, Institute of Legal Medicine, University of Campania "L. Vanvitelli", Via L. Armanni, 5, 80138 Napoli, Italy.

Fabio Policino (F)

Department of Advanced Biomedical Science, Legal Medicine Section, University of Naples "Federico II", Via S. Pansini, 5, 80138 Napoli, Italy.

Massimo Niola (M)

Department of Advanced Biomedical Science, Legal Medicine Section, University of Naples "Federico II", Via S. Pansini, 5, 80138 Napoli, Italy.

Carlo Pietro Campobasso (CP)

Forensic Toxicology Unit, Department of Experimental Medicine, University of Campania "L. Vanvitelli", Via L. Armanni, 5, 80138 Napoli, Italy.

Classifications MeSH