The Impact of RIPK1 Kinase Inhibition on Atherogenesis: A Genetic and a Pharmacological Approach.
RIPK1
atherosclerosis
necroptosis
Journal
Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304
Informations de publication
Date de publication:
28 Apr 2022
28 Apr 2022
Historique:
received:
28
03
2022
revised:
21
04
2022
accepted:
26
04
2022
entrez:
28
5
2022
pubmed:
29
5
2022
medline:
29
5
2022
Statut:
epublish
Résumé
RIPK1 (receptor-interacting serine/threonine-protein kinase 1) enzymatic activity drives both apoptosis and necroptosis, a regulated form of necrosis. Because necroptosis is involved in necrotic core development in atherosclerotic plaques, we investigated the effects of a RIPK1
Identifiants
pubmed: 35625752
pii: biomedicines10051016
doi: 10.3390/biomedicines10051016
pmc: PMC9138372
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Research Foundation - Flanders
ID : 11A2620N
Organisme : Research Foundation - Flanders
ID : EOS 30826052
Organisme : Hercules Foundation
ID : AUHA/13/03
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