Dyskerin Downregulation Can Induce ER Stress and Promote Autophagy via AKT-mTOR Signaling Deregulation.
DKC1
LC3 puncta
UPR
autophagic flux
dyskeratosis congenita
Journal
Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304
Informations de publication
Date de publication:
08 May 2022
08 May 2022
Historique:
received:
31
03
2022
revised:
28
04
2022
accepted:
04
05
2022
entrez:
28
5
2022
pubmed:
29
5
2022
medline:
29
5
2022
Statut:
epublish
Résumé
Dyskerin is an evolutionarily conserved nucleolar protein implicated in a wide range of fundamental biological roles, including telomere maintenance and ribosome biogenesis. Germline mutations of
Identifiants
pubmed: 35625829
pii: biomedicines10051092
doi: 10.3390/biomedicines10051092
pmc: PMC9138296
pii:
doi:
Types de publication
Journal Article
Langues
eng
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