The Mechanistic Perspective of Bilobetin Protective Effects against Cisplatin-Induced Testicular Toxicity: Role of Nrf-2/Keap-1 Signaling, Inflammation, and Apoptosis.
Cycas thouarsii
Ki67
bilobetin
caspase-3
cisplatin
keap-1
Journal
Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304
Informations de publication
Date de publication:
13 May 2022
13 May 2022
Historique:
received:
23
04
2022
revised:
08
05
2022
accepted:
12
05
2022
entrez:
28
5
2022
pubmed:
29
5
2022
medline:
29
5
2022
Statut:
epublish
Résumé
Cisplatin (CP) is a productive anti-tumor used to treat numerous tumors. However, multiple toxicities discourage prolonged use, especially toxicity on the reproductive system. This experiment was mapped out to determine the potential therapeutic impact of Bilobetin on CP-induced testicular damage. Herein, Bilobetin was isolated from
Identifiants
pubmed: 35625871
pii: biomedicines10051134
doi: 10.3390/biomedicines10051134
pmc: PMC9138600
pii:
doi:
Types de publication
Journal Article
Langues
eng
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