Performance Evaluation of a Rapid Antigen Test (RAT) during Omicron Pandemic Wave in Greece, Conducted by Different Personnel, and Comparison with Performance in Previous Wave (Alpha Variant) Period.
Omicron variant
SARS-CoV-2
evaluation
rapid antigen test
Journal
Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402
Informations de publication
Date de publication:
21 Apr 2022
21 Apr 2022
Historique:
received:
08
03
2022
revised:
12
04
2022
accepted:
18
04
2022
entrez:
28
5
2022
pubmed:
29
5
2022
medline:
29
5
2022
Statut:
epublish
Résumé
Due to the prevailing ambiguity regarding the performance of rapid antigen tests (RATs) for B.1.1.529 (Omicron) variant diagnosis, a commercial RAT was evaluated in the emergency ward of a general hospital in Larissa, Central Greece. The sampling and the evaluation were repeated twice by different personnel. Discordance between the two samplings was observed regarding the sensitivity (47.5%, 95% CI: 39.0-56.1 vs. 78.6%, 95% CI: 69.1-86.2) and specificity (93.8%, 95% CI: 86.0-97.9 vs. 100.0%, 95% CI: 93.3-100.0) of the RAT. Furthermore, the test displayed slightly lower sensitivity (78.6% vs. 85.5%, 95% CI: 79.1-90.5) compared to its initial evaluation that was conducted by our team when the B.1.1.7 (Alpha) variant was dominant.
Identifiants
pubmed: 35626204
pii: diagnostics12051048
doi: 10.3390/diagnostics12051048
pmc: PMC9139779
pii:
doi:
Types de publication
Journal Article
Langues
eng
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