Transmission Distortion of MCT1 rs1049434 among Polish Elite Athletes.
HWE
athletes
endurance
polymorphisms
speed
Journal
Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097
Informations de publication
Date de publication:
12 05 2022
12 05 2022
Historique:
received:
30
03
2022
revised:
04
05
2022
accepted:
09
05
2022
entrez:
28
5
2022
pubmed:
29
5
2022
medline:
1
6
2022
Statut:
epublish
Résumé
To date, nearly 300 genetic markers were linked to endurance and power/strength traits. The current study aimed to compare genotype distributions and allele frequencies of the common polymorphisms: The study involved 101 male elite Polish athletes and 41 healthy individuals from the Polish population as a control group. SNP data were extracted from whole-genome sequencing (WGS) performed using the following parameters: paired reads of 150 bps, at least 90 Gb of data per sample with 300 M reads and 30× mean coverage. All the analyzed polymorphisms conformed to Hardy-Weinberg equilibrium (HWE) in athletes and the control group, except the The
Sections du résumé
BACKGROUND
To date, nearly 300 genetic markers were linked to endurance and power/strength traits. The current study aimed to compare genotype distributions and allele frequencies of the common polymorphisms:
METHODS
The study involved 101 male elite Polish athletes and 41 healthy individuals from the Polish population as a control group. SNP data were extracted from whole-genome sequencing (WGS) performed using the following parameters: paired reads of 150 bps, at least 90 Gb of data per sample with 300 M reads and 30× mean coverage.
RESULTS
All the analyzed polymorphisms conformed to Hardy-Weinberg equilibrium (HWE) in athletes and the control group, except the
CONCLUSIONS
The
Identifiants
pubmed: 35627255
pii: genes13050870
doi: 10.3390/genes13050870
pmc: PMC9142056
pii:
doi:
Substances chimiques
Monocarboxylic Acid Transporters
0
Symporters
0
monocarboxylate transport protein 1
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Références
Br J Sports Med. 2004 Aug;38(4):418-21
pubmed: 15273174
J Sci Med Sport. 2015 Jan;18(1):114-8
pubmed: 24485392
Physiol Genomics. 2010 Mar 3;41(1):78-81
pubmed: 20028934
Eur J Appl Physiol. 2021 Dec;121(12):3399-3408
pubmed: 34480633
Int J Sports Physiol Perform. 2014 Jan;9(1):173-80
pubmed: 23628675
Genet Test Mol Biomarkers. 2013 Feb;17(2):99-103
pubmed: 23145508
Hum Biol. 1970 Dec;42(4):535-69
pubmed: 4928259
Nat Rev Genet. 2022 Jan;23(1):40-54
pubmed: 34522035
Nat Genet. 1993 Jun;4(2):108-10
pubmed: 8348144
Am Fam Physician. 2002 Mar 1;65(5):853-60
pubmed: 11898957
Genetics. 2001 Feb;157(2):885-97
pubmed: 11157005
Sports Med Open. 2015;1(1):33
pubmed: 26478856
J Hum Genet. 2015 Oct;60(10):641-5
pubmed: 26178432
Eur J Appl Physiol. 2020 Mar;120(3):665-673
pubmed: 31970519
Muscle Nerve. 2000 Jan;23(1):90-7
pubmed: 10590411
Am J Hum Genet. 2003 Sep;73(3):627-31
pubmed: 12879365
Genet Epidemiol. 2011 Nov;35(7):671-8
pubmed: 21818775
J Sci Med Sport. 2013 Mar;16(2):135-9
pubmed: 22749526
Front Physiol. 2021 Jul 21;12:694411
pubmed: 34366884
Sports Med. 2011 Jun 1;41(6):433-48
pubmed: 21615186
Int J Sports Med. 2007 Sep;28(9):717-21
pubmed: 17357964
J Clin Invest. 1990 Oct;86(4):1343-6
pubmed: 1976655
Int J Sports Med. 2017 Jan;38(1):76-80
pubmed: 27813046
J Physiol. 2011 Jul 1;589(Pt 13):3063-70
pubmed: 21540342
Front Genet. 2020 Jun 16;11:595
pubmed: 32612638
J Appl Physiol (1985). 2009 Jul;107(1):76-9
pubmed: 19478192
J Strength Cond Res. 2016 Apr;30(4):1171-6
pubmed: 26340466
Cell J. 2021 Jan;22(4):572-574
pubmed: 32347052
Biomed Res Int. 2017;2017:5313914
pubmed: 29362711
Biol Sport. 2021 Sep;38(3):465-474
pubmed: 34475628
Adv Clin Chem. 2015;70:247-314
pubmed: 26231489
Int J Sports Med. 2018 Dec;39(13):1028-1034
pubmed: 30290372
J Hum Kinet. 2019 Aug 21;68:17-36
pubmed: 31531130
Twin Res Hum Genet. 2007 Dec;10(6):812-20
pubmed: 18179392
J Cell Physiol. 2020 Mar;235(3):2139-2148
pubmed: 31392727
Int J Obes (Lond). 2007 Aug;31(8):1295-301
pubmed: 17342076
Physiol Genomics. 2008 Sep 17;35(1):45-54
pubmed: 18523157
Med Sport Sci. 2016;61:41-54
pubmed: 27287076
Exp Physiol. 2007 Sep;92(5):881-6
pubmed: 17631516
J Sci Med Sport. 2010 Sep;13(5):526-30
pubmed: 19850519
Gene. 2015 Dec 1;573(2):188-97
pubmed: 26358504
Nat Genet. 2010 Jul;42(7):565-9
pubmed: 20562875
Mutat Res. 2008 Jul-Aug;659(1-2):31-9
pubmed: 18164232
Genome Med. 2021 Feb 22;13(1):31
pubmed: 33618777
Sports Med. 2013 Sep;43(9):803-17
pubmed: 23681449
J Appl Physiol (1985). 1999 Oct;87(4):1313-6
pubmed: 10517757
Biol Sport. 2021 Jun;38(2):229-234
pubmed: 34079167
Genes Dev. 2004 Feb 15;18(4):357-68
pubmed: 15004004