Oxidative Stress Status in Post Stroke Patients: Sex Differences.
Oxidative Status Index (OSI)
antioxidant defense
hydroperoxides
oxidative stress
rehabilitation
stroke
Journal
Healthcare (Basel, Switzerland)
ISSN: 2227-9032
Titre abrégé: Healthcare (Basel)
Pays: Switzerland
ID NLM: 101666525
Informations de publication
Date de publication:
09 May 2022
09 May 2022
Historique:
received:
06
04
2022
revised:
03
05
2022
accepted:
06
05
2022
entrez:
28
5
2022
pubmed:
29
5
2022
medline:
29
5
2022
Statut:
epublish
Résumé
After a cerebral stroke insult, there is an overproduction of Reactive Oxygen Species (ROS), which overcome the antioxidant defenses, causing further tissues damage. The status of oxidative stress in stroke patients over time, particularly in those undergoing rehabilitation treatments, has been poorly investigated. We analyzed the oxidative stress status in 61 subacute stroke patients (33 females and 28 males) admitted to our rehabilitation center by measuring, in serum: hydroperoxides levels (d-ROMs), antioxidant activity (BAP test), and the relative antioxidant capacity (OSI index). We also analyzed patients for glucose levels and lipid profile. In addition, we analyzed the correlation between oxidative stress status biomarkers and motor deficits, disability, and pain. Almost all patients showed high or very high levels of d-ROMs, while BAP levels were apparently in the reference range of normality. Females had lower BAP values (females: 2478 ± 379; males: 2765 ± 590;
Identifiants
pubmed: 35628006
pii: healthcare10050869
doi: 10.3390/healthcare10050869
pmc: PMC9140331
pii:
doi:
Types de publication
Journal Article
Langues
eng
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