The Association between Single Nucleotide Polymorphisms, including miR-499a Genetic Variants, and Dyslipidemia in Subjects Treated with Pharmacological or Phytochemical Lipid-Lowering Agents.

Aryldialkylphosphatase / genetics Cardiovascular Diseases / drug therapy Dyslipidemias / drug therapy Humans Hypolipidemic Agents / pharmacology Lipid Metabolism / drug effects MicroRNAs / genetics Phytochemicals / pharmacology Polymorphism, Single Nucleotide
blood lipids cardiovascular risk dyslipidemia miR-499a nutraceutical single nucleotide polymorphism statins

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
17 May 2022
Historique:
received: 24 04 2022
revised: 13 05 2022
accepted: 15 05 2022
entrez: 28 5 2022
pubmed: 29 5 2022
medline: 1 6 2022
Statut: epublish

Résumé

Disorders of lipoprotein metabolism are among the major risk factors for cardiovascular disease (CVD) development. Single nucleotide polymorphisms (SNPs) have been associated with the individual variability in blood lipid profile and response to lipid-lowering treatments. Here, we genotyped 34 selected SNPs located in coding genes related to lipid metabolism, inflammation, coagulation, and a polymorphism in the

Identifiants

DOI: 10.3390/ijms23105617 PMID: 35628426 PMC: PMC9145435
pubmed: 35628426
pii: ijms23105617
doi: 10.3390/ijms23105617
pmc: PMC9145435
pii:
doi:

Substances chimiques

Hypolipidemic Agents 0
MIRN499 microRNA, human 0
MicroRNAs 0
Phytochemicals 0
Aryldialkylphosphatase EC 3.1.8.1

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Università Politecnica delle Marche
ID : RSA Grant
Organisme : Ministero della Salute
ID : Ricerca Corrente to IRCCS INRCA

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Auteurs

Angelica Giuliani (A)

Department of Clinical and Molecular Sciences, DISCLIMO, Università Politecnica delle Marche, 60126 Ancona, Italy.
ORCID: 0000-0002-8477-8519

Alberto Montesanto (A)

Department of Biology, Ecology and Earth Sciences, University of Calabria, 87036 Rende, Italy.

Giulia Matacchione (G)

Department of Clinical and Molecular Sciences, DISCLIMO, Università Politecnica delle Marche, 60126 Ancona, Italy.

Laura Graciotti (L)

Department of Excellence SBSP-Biomedical Sciences and Public Health, Università Politecnica delle Marche, 60126 Ancona, Italy.
ORCID: 0000-0002-1874-5217

Deborah Ramini (D)

Center of Clinical Pathology and Innovative Therapy, IRCCS INRCA, 60121 Ancona, Italy.
ORCID: 0000-0001-8925-8195

Olga Protic (O)

Cardiology Unit, IRCCS INRCA, 60127 Ancona, Italy.
ORCID: 0000-0002-1936-6139

Roberta Galeazzi (R)

Clinical Laboratory and Molecular Diagnostic, IRCCS INRCA, 60127 Ancona, Italy.
ORCID: 0000-0002-7997-8794

Roberto Antonicelli (R)

Cardiology Unit, IRCCS INRCA, 60127 Ancona, Italy.

Elena Tortato (E)

Metabolic Diseases and Diabetology Department, IRCCS INRCA, 60127 Ancona, Italy.

Anna Rita Bonfigli (AR)

Scientific Direction, IRCCS INRCA, 60124 Ancona, Italy.
ORCID: 0000-0002-9619-0181

Jacopo Sabbatinelli (J)

Department of Clinical and Molecular Sciences, DISCLIMO, Università Politecnica delle Marche, 60126 Ancona, Italy.
Laboratory Medicine Unit, Azienda Ospedaliero Universitaria Ospedali Riuniti, 60126 Ancona, Italy.
ORCID: 0000-0001-9947-6778

Fabiola Olivieri (F)

Department of Clinical and Molecular Sciences, DISCLIMO, Università Politecnica delle Marche, 60126 Ancona, Italy.
Center of Clinical Pathology and Innovative Therapy, IRCCS INRCA, 60121 Ancona, Italy.
ORCID: 0000-0002-9606-1144

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Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Esterases › Phosphoric triester hydrolases › Aryldialkylphosphatase › The Association between Single Nucleotide...
questionsmedicales.fr › Maladies cardiovasculaires › The Association between Single Nucleotide...
questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Maladies métaboliques › Troubles du métabolisme lipidique › Dyslipidémies › The Association between Single Nucleotide...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › The Association between Single Nucleotide...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents régulateurs du métabolisme des lipides › Hypolipémiants › The Association between Single Nucleotide...
questionsmedicales.fr › Métabolisme › Métabolisme lipidique › The Association between Single Nucleotide...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN non traduit › Petit ARN non traduit › microARN › The Association between Single Nucleotide...
questionsmedicales.fr › Facteurs biologiques › Composés phytochimiques › The Association between Single Nucleotide...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Polymorphisme génétique › Polymorphisme de nucléotide simple › The Association between Single Nucleotide...