Cardiovascular Disease Risk in Rheumatoid Arthritis Anno 2022.
cardiovascular diseases
cardiovascular risk management
inflammation
rheumatoid arthritis
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
11 May 2022
11 May 2022
Historique:
received:
15
02
2022
revised:
02
05
2022
accepted:
05
05
2022
entrez:
28
5
2022
pubmed:
29
5
2022
medline:
29
5
2022
Statut:
epublish
Résumé
The risk for developing cardiovascular diseases (CVD) in rheumatoid arthritis (RA) patients is 1.5 times higher compared to the general population. This risk is partly due to the contribution of systemic inflammation in increased atherogenesis, while an increased prevalence of "traditional" cardiovascular risk factors, such as hypertension and dyslipidemia, is also attributed to nearly 50% of the total CVD risk. Most anti-rheumatic medication partly reduces this CVD risk, primarily by reducing inflammation. The increased risk is recognized by most guidelines, which advise consequent screening and multiplying calculated risk scores by 1.5. However, screening in daily clinical practice is poorly done, and RA patients often have undiagnosed and untreated risk factors. In conclusion, even nowadays, RA patients still have an increased risk of developing CVD. Advances in anti-inflammatory treatment partly mitigate this risk, but RA patients need mandatory screening for CV risk factors to turn their CVD risk towards that of the general population.
Identifiants
pubmed: 35628831
pii: jcm11102704
doi: 10.3390/jcm11102704
pmc: PMC9142998
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Références
Arthritis Rheum. 2008 Dec 15;59(12):1690-7
pubmed: 19035419
PLoS One. 2017 Mar 23;12(3):e0170361
pubmed: 28333949
Joint Bone Spine. 2011 Mar;78(2):179-83
pubmed: 20851020
Lancet. 2013 Aug 31;382(9894):769-79
pubmed: 23726390
Exp Ther Med. 2020 Oct;20(4):3498-3503
pubmed: 32905201
Ann Rheum Dis. 2021 Mar;80(3):304-311
pubmed: 33115760
Autoimmun Rev. 2018 Apr;17(4):399-404
pubmed: 29452240
Arthritis Rheum. 2006 Aug 15;55(4):531-6
pubmed: 16874796
J Am Heart Assoc. 2017 Mar 13;6(3):
pubmed: 28288972
Eur Heart J. 2021 Nov 7;42(42):4389-4400
pubmed: 34343257
Ann Rheum Dis. 2021 Sep;80(9):1130-1136
pubmed: 33827788
J Rheumatol. 2019 Apr;46(4):370-375
pubmed: 30504507
Eur Heart J. 2021 Sep 7;42(34):3227-3337
pubmed: 34458905
Curr Pharm Des. 2012;18(11):1502-11
pubmed: 22364134
Ann Rheum Dis. 2017 Jan;76(1):17-28
pubmed: 27697765
J Korean Med Sci. 2016 Feb;31(2):202-7
pubmed: 26839473
J Am Heart Assoc. 2018 Jan 24;7(3):
pubmed: 29367417
Biochemistry (Mosc). 2016 Nov;81(11):1358-1370
pubmed: 27914461
J Inflamm Res. 2020 Sep 14;13:519-531
pubmed: 32982367
Arthritis Res Ther. 2014 Mar 05;16(2):R61
pubmed: 24594022
Nat Rev Rheumatol. 2022 May;18(5):301-304
pubmed: 35318462
Ann Rheum Dis. 2021 Dec;80(12):1522-1529
pubmed: 34215644
Diabetes Care. 2005 Jul;28(7):1769-78
pubmed: 15983333
N Engl J Med. 2016 Dec 29;375(26):2519-29
pubmed: 27959716
RMD Open. 2015 May 21;1(1):e000080
pubmed: 26535138
Clin Rheumatol. 2021 Nov;40(11):4457-4471
pubmed: 34554329
Eur Heart J. 2017 Dec 21;38(48):3545-3548
pubmed: 29281019
Nat Rev Immunol. 2013 Oct;13(10):709-21
pubmed: 23995626
N Engl J Med. 2022 Jan 27;386(4):316-326
pubmed: 35081280
Rheumatol Int. 2021 May;41(5):863-877
pubmed: 33175207
BMJ. 2006 Jun 3;332(7553):1302-8
pubmed: 16740558
Annu Rev Immunol. 2009;27:165-97
pubmed: 19302038
Nat Rev Immunol. 2022 Apr;22(4):251-265
pubmed: 34389841
Lancet Rheumatol. 2020 Oct;2(10):e583-e585
pubmed: 33106791
J Am Heart Assoc. 2015 Jan 30;4(2):
pubmed: 25637346
J Am Heart Assoc. 2016 Jan 04;5(1):
pubmed: 26727968
J Lipid Res. 2015 May;56(5):1034-42
pubmed: 25713100
Rheumatology (Oxford). 2021 Mar 2;60(3):1400-1409
pubmed: 32984893
Ann Rheum Dis. 2005 Feb;64(2):303-5
pubmed: 15231512
JAMA. 2007 Jul 11;298(2):187-93
pubmed: 17622600
Musculoskeletal Care. 2011 Jun;9(2):69-74
pubmed: 21618398
Ann Rheum Dis. 2010 Jan;69(1):70-81
pubmed: 19174392
Clin Res Cardiol Suppl. 2017 Mar;12(Suppl 1):31-37
pubmed: 28188431
Scand J Rheumatol. 2019 Sep;48(5):345-352
pubmed: 31210083
Curr Opin Rheumatol. 2021 May 1;33(3):300-306
pubmed: 33767091
Curr Opin Lipidol. 2017 Feb;28(1):52-59
pubmed: 27906712
Neth Heart J. 2017 Apr;25(4):231-242
pubmed: 28194698
Rheumatology (Oxford). 2016 Jul;55(7):1210-6
pubmed: 27009825
Ann Rheum Dis. 2015 Jun;74(6):998-1003
pubmed: 24458537
Maedica (Bucur). 2010 Dec;5(4):286-91
pubmed: 21977172
Arthritis Rheum. 2008 Dec;58(12):3675-83
pubmed: 19035488
J Transl Int Med. 2020 Jun 30;8(2):99-105
pubmed: 32983932
Nat Rev Immunol. 2003 Sep;3(9):745-56
pubmed: 12949498
Arthritis Res Ther. 2006;8(5):R151
pubmed: 16984661
Nat Rev Rheumatol. 2021 May;17(5):270-290
pubmed: 33833437
Can J Cardiol. 2020 Nov;36(11):1739-1746
pubmed: 32603700
Rheumatology (Oxford). 2009 Oct;48(10):1309-13
pubmed: 19696061
Ther Adv Musculoskelet Dis. 2021 Aug 26;13:1759720X211030809
pubmed: 34471426
J Rheumatol. 2021 May;48(5):648-655
pubmed: 32801134
J Clin Pharm Ther. 2017 Jun;42(3):356-362
pubmed: 28440561
Int J Cardiol. 2017 Aug 1;240:20-24
pubmed: 28487154
Arthritis Care Res (Hoboken). 2019 Aug;71(8):1004-1018
pubmed: 30175897
J Intern Med. 2015 Nov;278(5):483-93
pubmed: 26260307
Ann Rheum Dis. 2015 Mar;74(3):480-9
pubmed: 25561362
Arq Bras Cardiol. 2021 Mar;116(3):443-451
pubmed: 33909773
Ann Rheum Dis. 2012 Jun;71(6):862-8
pubmed: 22267329
Arthritis Rheumatol. 2017 Jun;69(6):1154-1164
pubmed: 28245350
N Engl J Med. 2019 Feb 21;380(8):752-762
pubmed: 30415610
Rheumatology (Oxford). 2022 Apr 08;:
pubmed: 35394013
Ther Adv Musculoskelet Dis. 2018 Jun;10(5-6):117-127
pubmed: 29942363
Arthritis Rheumatol. 2015 Jun;67(6):1449-55
pubmed: 25776112
Rheumatology (Oxford). 2005 May;44(5):677-80
pubmed: 15784627
Am J Med. 2013 Aug;126(8):730.e9-730.e17
pubmed: 23885678
Arthritis Care Res (Hoboken). 2015 Feb;67(2):169-79
pubmed: 25074725
Rheumatology (Oxford). 2011 Mar;50(3):518-31
pubmed: 21071477
Rheumatology (Oxford). 2017 Jul 1;56(7):1102-1110
pubmed: 28339992
Ann Rheum Dis. 2018 Jan;77(1):48-54
pubmed: 28877868
J Am Heart Assoc. 2014 Oct 21;3(5):e001267
pubmed: 25336464
Biomed Res Int. 2014;2014:406960
pubmed: 25136585
Rheum Dis Clin North Am. 1997 Nov;23(4):739-55
pubmed: 9361153
Curr Opin Physiol. 2021 Feb;19:92-98
pubmed: 33073072
Int J Prev Med. 2014 Aug;5(8):927-46
pubmed: 25489440
Medicine (Baltimore). 2021 Feb 19;100(7):e24579
pubmed: 33607787
Arthritis Res Ther. 2017 May 31;19(1):113
pubmed: 28569219