Goal-Directed Fluid Therapy Enhances Gastrointestinal Recovery after Laparoscopic Surgery: A Systematic Review and Meta-Analysis.

enhanced recovery after surgery goal-directed fluid therapy haemodynamic monitoring intraoperative fluid management laparoscopic abdominal surgery perioperative care

Journal

Journal of personalized medicine
ISSN: 2075-4426
Titre abrégé: J Pers Med
Pays: Switzerland
ID NLM: 101602269

Informations de publication

Date de publication:
30 Apr 2022
Historique:
received: 08 04 2022
revised: 26 04 2022
accepted: 27 04 2022
entrez: 28 5 2022
pubmed: 29 5 2022
medline: 29 5 2022
Statut: epublish

Résumé

(1) Background: Whether goal-directed fluid therapy (GDFT) provides any outcome benefit as compared to non-goal-directed fluid therapy (N-GDFT) in elective abdominal laparoscopic surgery has not been determined yet. (2) Methods: A systematic literature search was conducted in MEDLINE, Embase, CENTRAL, Web of Science, and Scopus. The main outcomes were length of hospital stay (LOHS), time to first flatus and stool, intraoperative fluid and vasopressor requirements, serum lactate levels, and urinary output. Pooled risks ratios (RRs) with 95% confidence intervals (CI) were calculated for dichotomous outcomes and weighted mean difference (WMD) with 95% CI for continuous outcomes. (3) Results: Eleven studies were included in the quantitative, and fifteen in the qualitative synthesis. LOHS (WMD: -1.18 days, 95% CI: -1.84 to -0.53) and time to first stool (WMD: -9.8 h; CI -12.7 to -7.0) were significantly shorter in the GDFT group. GDFT resulted in significantly less intraoperative fluid administration (WMD: -441 mL, 95% CI: -790 to -92) and lower lactate levels at the end of the operation: WMD: -0.25 mmol L

Identifiants

pubmed: 35629156
pii: jpm12050734
doi: 10.3390/jpm12050734
pmc: PMC9143059
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Subventions

Organisme : Economic Development and Innovation Operational Programme Grant
ID : GINOP-2.3.2-15-2016-00048 - STAY ALIVE
Organisme : Hungarian National Research, Development and Innovation Office
ID : K 138816

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Auteurs

Marcell Virág (M)

Szentágothai Research Centre, Institute for Translational Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.
Department of Anesthesiology and Intensive Therapy, Szent György University Teaching Hospital of Fejér County, 8000 Székesfehérvár, Hungary.
Doctoral School of Clinical Medicine, University of Szeged, 6720 Szeged, Hungary.

Máté Rottler (M)

Szentágothai Research Centre, Institute for Translational Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.
Department of Anesthesiology and Intensive Therapy, Szent György University Teaching Hospital of Fejér County, 8000 Székesfehérvár, Hungary.
Doctoral School of Clinical Medicine, University of Szeged, 6720 Szeged, Hungary.

Noémi Gede (N)

Szentágothai Research Centre, Institute for Translational Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.

Klementina Ocskay (K)

Szentágothai Research Centre, Institute for Translational Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.
Centre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary.

Tamás Leiner (T)

Szentágothai Research Centre, Institute for Translational Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.
Anaesthetic Department, Hinchingbrooke Hospital, North West Anglia NHS Foundation Trust, Huntingdon PE29 6NT, UK.

Máté Tuba (M)

Szentágothai Research Centre, Institute for Translational Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.

Szabolcs Ábrahám (S)

Szentágothai Research Centre, Institute for Translational Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.

Nelli Farkas (N)

Szentágothai Research Centre, Institute for Translational Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.

Péter Hegyi (P)

Szentágothai Research Centre, Institute for Translational Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.
Centre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary.
Division for Pancreatic Disorders, Heart and Vascular Center, Semmelweis University, 1122 Budapest, Hungary.

Zsolt Molnár (Z)

Szentágothai Research Centre, Institute for Translational Medicine, Medical School, University of Pécs, 7624 Pécs, Hungary.
Doctoral School of Clinical Medicine, University of Szeged, 6720 Szeged, Hungary.
Centre for Translational Medicine, Semmelweis University, 1085 Budapest, Hungary.
Department of Anaesthesiology and Intensive Therapy, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Department of Anaesthesiology and Intensive Therapy, Semmelweis University, 1082 Budapest, Hungary.

Classifications MeSH