Serum and Synovial Markers in Patients with Rheumatoid Arthritis and Periprosthetic Joint Infection.

arthroplasty periprosthetic joint infection rheumatoid arthritis total hip replacement total knee replacement

Journal

Journal of personalized medicine
ISSN: 2075-4426
Titre abrégé: J Pers Med
Pays: Switzerland
ID NLM: 101602269

Informations de publication

Date de publication:
17 May 2022
Historique:
received: 08 04 2022
revised: 11 05 2022
accepted: 12 05 2022
entrez: 28 5 2022
pubmed: 29 5 2022
medline: 29 5 2022
Statut: epublish

Résumé

Current diagnostic standards for PJI rely on inflammatory markers that are typically elevated in autoimmune diseases, thus making the diagnosis of PJI in patients with rheumatoid arthritis and joint replacement particularly complicated. There is a paucity of data on differentiating PJI from rheumatoid arthritis in patients with previous arthroplasty. In this study, we retrospectively analyzed the cases of 17 patients with rheumatoid arthritis and 121 patients without rheumatoid disease who underwent surgical intervention due to microbiology-positive PJI of the hip or knee joint. We assessed clinical patient characteristics, laboratory parameters, and prosthesis survival rates in patients with and without rheumatoid arthritis and acute or chronic PJI. ROC analysis was conducted for the analyzed parameters. In patients with chronic PJI, peripheral blood CRP (

Identifiants

pubmed: 35629231
pii: jpm12050810
doi: 10.3390/jpm12050810
pmc: PMC9148028
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Yi Ren (Y)

Center for Musculoskeletal Surgery, Clinic for Orthopedics, Charité University Hospital, 10117 Berlin, Germany.

Lara Biedermann (L)

Center for Musculoskeletal Surgery, Clinic for Orthopedics, Charité University Hospital, 10117 Berlin, Germany.

Clemens Gwinner (C)

Center for Musculoskeletal Surgery, Clinic for Orthopedics, Charité University Hospital, 10117 Berlin, Germany.

Carsten Perka (C)

Center for Musculoskeletal Surgery, Clinic for Orthopedics, Charité University Hospital, 10117 Berlin, Germany.

Arne Kienzle (A)

Center for Musculoskeletal Surgery, Clinic for Orthopedics, Charité University Hospital, 10117 Berlin, Germany.
Berlin Institute of Health, Charité-Universitätsmedizin Berlin, BIH Biomedical Innovation Academy, BIH Charité Clinician Scientist Program, Charitéplatz 1, 10117 Berlin, Germany.

Classifications MeSH