Role of Uncoupling Protein 2 Gene Polymorphisms on the Risk of Ischemic Stroke in a Sardinian Population.
Sardinians
genetic association
ischemic stroke
uncoupling protein 2
vascular disease
Journal
Life (Basel, Switzerland)
ISSN: 2075-1729
Titre abrégé: Life (Basel)
Pays: Switzerland
ID NLM: 101580444
Informations de publication
Date de publication:
12 May 2022
12 May 2022
Historique:
received:
29
03
2022
revised:
02
05
2022
accepted:
09
05
2022
entrez:
28
5
2022
pubmed:
29
5
2022
medline:
29
5
2022
Statut:
epublish
Résumé
The mitochondrial uncoupling protein 2 (UCP2) acts as an anion transporter and as an antioxidant factor able to reduce the reactive oxygen species level. Based on its effects, UCP2 prevents the membrane lipids, proteins, and DNA damage while preserving normal cellular functions. Many variants have been identified within the human
Identifiants
pubmed: 35629388
pii: life12050721
doi: 10.3390/life12050721
pmc: PMC9147365
pii:
doi:
Types de publication
Journal Article
Langues
eng
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